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时间:2020-05-23
《联合肝脏离断和门静脉结扎二步肝切除术治疗肝硬化肝癌疗效分析(附1例报告).pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、20l4年8月第34卷第8-739·论著文章编号:1005—2208(2014)08—0739—05DOI:10.7504/CJPS.ISSNl005—2208.2014.08.19联合肝脏离断和门静脉结扎二步肝切除术治疗肝硬化肝癌疗效分析(附1例报告)洪德飞,刘合春,彭淑牖,陈伟力,胡秋灵。,张远标,邹勇。,成剑,淦勤,吴兆平2王知非,黄东胜,欧阳霆【摘要】目的探讨联合肝脏离断和门静脉结扎二步肝切除术(ALPPS)在合并肝硬化的肝细胞性肝癌中的应用价值。方法对2014—03—07浙江省人民医院肝胆胰外科收治的1例合并肝硬化的右肝巨块性肝癌病人行ALPPS治疗,并对围手
2、术期指标进行分析。手术方案:原位前入路离断左肝外侧叶和内侧叶后,肝劈离面用人工血管材料缝合覆盖,结扎门静脉右支;术后15d,顺、逆法行肝右三叶切除术。结果第l步术前剩余肝脏体积(左肝外叶)460.8mL,第2步术前增大至760.2mL,增加65.0%。标准全肝体积1019_3mI,第l步术前标准剩余肝体积320mI/m,第2步术前527.9mL/m;标准剩余肝体积占标准全肝体积分别为31-4%和52.0%。第1步和第2步手术时间分别为188min和124nlin;术中出血分别为2000mL和400mL;术后恢复肝功能时间分别为6d和4d第l步术后并发胆瘘和少量腹水、右上
3、肺小动脉部分栓塞;第2步术后无并发症,术后10d出院。结论ALPPS为剩余肝体积不足的合并肝硬化的肝细胞性肝癌提供了新的治疗选择。【关键词】肝硬化;原发性肝癌;剩余肝脏体积;二步肝切除术;门静脉结扎中图分类号:R6文献标志码:AAssociatingliverpartitionandportalveinligationforstagedhepatectomyforHCCwithlivercirrhosis:Areportof1caseHONGDe-fei,LIUHe—chun,PENGShu—you,eta1.Departmento/‘Hepatobiliarypanc
4、reaticSurgery,ZhejiangProvincialPeople’sHospital,Hangzhou310014,ChinaCorrespondingauthor:HONGDe币,E—mail:hongdefi@163.comAbstractObjectiveTodiscussthesafetyandeffectivenessofassociatingliverpartitionandportalveinligationforstagedhepatectomy(ALPPS)inhepatocellularcarcinomacomplicatedwithli
5、vercirrhosis.MethodsALPPSwasperformedfor1casesofhugeHCConrightlivercomplicatedwithlivercirrhosisonMarch7,2014inDepartmentofHepatobiliarypancreaticSurgery,ZhejiangProvincialPeople’sHospita1.Dataofperioperativeperiodwererecordedandanalyzed.Thesurgicalplanincludes:first,SlI,SmandSIVsegmentw
6、eredissectedwithananteriorinsituapproach一andfightportalveinwasligated.After15days.acombinationofantegradeandretrogradeapproachwereappliedinrightliverlobectomy.ResultsTheremnantlivervolumewas460.8mLbe~rethefirststepofoperation,whichwasincreasedby65.0%to760.2mLhe'rethesecondstepofoperation
7、.Thestandardwholelivervolumewas1019.3mL.Thestandardremnantlivervolumewas320mL/m。beforethefirststepofoperation,andwas527.9mL/mbeforethesecondstepofoperation.whichaccountedfor31.4%and52.0%ofthestandardwholelivervolumerespectively.Theoperativetimeforthefirststepandsecondstep
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