不明原因肝损害的诊断特点和肝组织病理特征115例-论文.pdf

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2、导隼^滔化奈盎．@世界华人消化杂志2014年4月2813；2(12)：1730—1733wcjd@wjgnet．cornISSN1009—3079(print)ISSN2219—2859(online)÷善一踊嘴睡cE—j舞嚣搿蓦蠢蕊善不明原因肝损害的诊断特点和肝组织病理特征115例陈学平，罗志刚，曹丽玲，杨姝，张琳英，尤丽英，杨晋辉，唐映梅Thebiochemicalandimmunologicalfeatures，aswellasvirusmarkers,abdominalimagingfindingsandhepatich

3、istopathologywereanalyzed．RESULTS：Adefinitediagnosiswasachievedbyliverbiopsyin109patients．Amongthem,38werediagnosedwithprimarybiliarycirrhosis(PBC)，andthemainpathologicalfeaturewas一曼non—suppurativeinflammationinthebileduct；31withautoimmunehepatitis(AIH)，whichshowedobvi

4、ousinterfaceinflammationinlivertissue；27withnonalcoholicfatt、，liverdisease(NAFLD)，whichshowedvisiblehepaticsteato—sisandballooningdegeneration；4withoccultDiagnosticcharacteristicsandhepatitisB，whichpresentedwithportalinflam—hepatichiStopathoIogyin115mationandinfiltrati

5、onoflymphocytesandwerepositiveforHBcAgand／orHBsAgasrevealedpatientswithliverinjuryofbyimmunohistochemistry；2withhepaticamy-tinknownreasons1oidosis，whichshowedalotofeosinamyloiddepositsreactivewithCongoredinlivercellsXue—PingChenZhi-GangLuoLi-LingCaolShuYang

6、Lin-YingZha

7、ngILi-YingYou

8、Jin-HuiYang

9、andbloodsinus；2withhemochromatosis，Ying-MeiTangwhichshowedobviousironpigmentdepositioninlivercells；2withglycogenstoragedisease，Xue。PingChen，Zhi‘GangLuo，Li-LingCao，ShuYang，whichshowedextensivehyalinedegenerationinLin-YingZhang，DepartmentofGastr

10、oenterology,theFirsthepaticcellsandwaspositiveforDpas；1withPeople’sHospitalofKunming．Kunming650011．YunnanschistosomiasiswithschistosomeeggsdetectedProvince，ChinaLi-yingYou，DepartmentofGeriatrics，theFirstPeople’smicroscopically；1withtoxoplasmosis，andelec—HospitalofKunmi

11、ng，Kunming650011，YunnanProvince，tronmicroscopyrevealedToxoplasmagondiiChinarhoptry；1withDubin-Johnsonsyndrome，which3in-Hui’Ylang，Ying-Mei‘ranq，DepartmentofHepatopan．creatobiliary,theSecondAffiliatedHospitalofKunmingshowedthick，darkbrownpigmentparticlesinMedicalUniversi

12、ty,Kunming650101．YunnanProvince．livercells．Therewerestill6casesinwhomaChinadefinitediagnosiscouldnotbeachievedafterSu