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时间:2020-05-15
《甲氨蝶呤经阴道注水腹腔镜治疗输卵管妊娠的效果观察.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·妇幼医学·中国当代医药2015年4月第22卷第10期甲氨蝶呤经阴道注水腹腔镜治疗输卵管妊娠的效果观察徐君容林丽群黄东斌广东省惠州市龙门县人民医院妇产科,广东龙门516800【摘要】目的观察甲氨蝶呤(MTX)经阴道注水腹腔镜(THL)治疗输卵管妊娠的临床效果。方法本院2010年7月~2013年1O月收治的82例输卵管妊娠患者根据随机数字表法分为两组,对照组(n=40)采用肌内注射MTX治疗,观察组(n=42)采用MTXTHL治疗。记录观察组手术情况,比较两组治愈率、血清13一HCG水平下降至正常范围时间、不良反应发生率、住院天数、住院费用、1
2、周后妊娠包块大小、输卵管再通率。结果THL平均手术操作时间为(26.1±4.4)rain,后穹隆穿刺成功率100%。与术前输卵管妊娠诊断完全符合,术中未发生并发症,术中发现有4例对侧输卵管阻塞现象。观察组治愈率明显高于对照组(户l<0.05),不良反应发生率低于对照组(P<0.05),住院天数明显短于对照组(PO.05);观察组血B—HCG下降至正常时间明显快于对照组(尸3、注射治疗输卵管妊娠安全有效。值得临床推广应用。【关键词】甲氨蝶呤;经阴道注水腹腔镜;输卵管妊娠【中图分类号】R714.22【文献标识码】A【文章编号】1674—4721(2015)04(a)一0106—03EfectobservationofmethotrexatetransvaginalhydrOlapar0scOpyinthetreatmentoftubalpregnancyxuJun——rongLINLi——qunHUANGDong-binDepartmentofGynecologyandObstetrics,PeoplesHospit4、alinLongmenCountyofHuizhouCityinGuangdongProvince,Longmen516800,China[AbstractJObjectiveToobservetheclinicaleffectofmethotrexatefMTX)transvaginalhydrolaparoscopy(THL)inthetreatmentoftubalpregnancy.Methods82patientsoftubalpregnancyinourhospitalfromJuly2010toOctober2013werera5、ndomlydividedintotwogroupsaccordingtothedigitalmetermethod,MTXbyintramuscularinjectionwasusedincontrolgroup(n=40),andMTXbyTHLwasappliedinobservationgroup(n=42).Theoperationsituationinobservationgroupwasrecorded.Thecurerate,thetimeofserumB—HCGdecreasedtonormalrange,theincide6、ncerateofadversereaction,hospitalizationdayandhospitalizationexpense,thesizeofpregnancymass1weekaftertreatment,rateoffallopi—antubebetweentwogroupswerecompared.ResultsTheaveragetimeofTHLoperationwas(26.1+4.4)min,thesuccessrateofpunctureinposteriorfornixwas100%,certainlyinpr7、eoperativediagnosisoftubalpregnancy,andhadnocompli—cationintreatment.4casesofthecontralateralfallopiantubeobstructionphenomenaweref0undintreatment.Thecurerateofobservationgroupwassignificantlyhigherthanthatofcontrolgroup(P8、ongroupwaslowerthanthatincontrolgroup(P<0.05),hospitalizationdayofobservationgroup
3、注射治疗输卵管妊娠安全有效。值得临床推广应用。【关键词】甲氨蝶呤;经阴道注水腹腔镜;输卵管妊娠【中图分类号】R714.22【文献标识码】A【文章编号】1674—4721(2015)04(a)一0106—03EfectobservationofmethotrexatetransvaginalhydrOlapar0scOpyinthetreatmentoftubalpregnancyxuJun——rongLINLi——qunHUANGDong-binDepartmentofGynecologyandObstetrics,PeoplesHospit
4、alinLongmenCountyofHuizhouCityinGuangdongProvince,Longmen516800,China[AbstractJObjectiveToobservetheclinicaleffectofmethotrexatefMTX)transvaginalhydrolaparoscopy(THL)inthetreatmentoftubalpregnancy.Methods82patientsoftubalpregnancyinourhospitalfromJuly2010toOctober2013werera
5、ndomlydividedintotwogroupsaccordingtothedigitalmetermethod,MTXbyintramuscularinjectionwasusedincontrolgroup(n=40),andMTXbyTHLwasappliedinobservationgroup(n=42).Theoperationsituationinobservationgroupwasrecorded.Thecurerate,thetimeofserumB—HCGdecreasedtonormalrange,theincide
6、ncerateofadversereaction,hospitalizationdayandhospitalizationexpense,thesizeofpregnancymass1weekaftertreatment,rateoffallopi—antubebetweentwogroupswerecompared.ResultsTheaveragetimeofTHLoperationwas(26.1+4.4)min,thesuccessrateofpunctureinposteriorfornixwas100%,certainlyinpr
7、eoperativediagnosisoftubalpregnancy,andhadnocompli—cationintreatment.4casesofthecontralateralfallopiantubeobstructionphenomenaweref0undintreatment.Thecurerateofobservationgroupwassignificantlyhigherthanthatofcontrolgroup(P8、ongroupwaslowerthanthatincontrolgroup(P<0.05),hospitalizationdayofobservationgroup
8、ongroupwaslowerthanthatincontrolgroup(P<0.05),hospitalizationdayofobservationgroup
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