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时间:2020-05-22
《静脉应用胺碘酮与西地兰对快速阵发性房颤的疗效比较-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、口固⋯删论著静脉应用胺碘酮与西地兰对快速阵发性房颤的疗效比较李妍山东省东营市胜利石油管理局孤岛医院内一科,山东东营257231【摘要】目的比较静脉推注胺碘酮与西地兰治疗快速阵发性房颤的疗效差异。方法选择92例快速阵发性房颤患者,随机分为胺碘酮组和西地兰组各46例,分别静推胺碘酮和西地兰,观察房颤的转复、心室率变化及不良反应。结果胺碘酮组与西地兰组的治疗有效率分别为82.61%和58.70%,差异有统计学意义(P2、(P<0.05)。结论静脉应用胺碘酮治疗快速阵发性房颤,疗效优于西地兰,不良反应轻,值得推广。【关键词】心房颤动;胺碘酮;西地兰【中图分类号】R4【文献标识码】A【文章编号】1674—0742(2014)07(b)一0008—02ComparisonoftheClinicalEficacyBetweenAmiodaroneandCedilanidintheTreatmentofRapidParoxysmalAtrialFibrillationthIntravenousAd·ministrationLIYonTheFirstDep3、artmentofInternalMedicine,GudaoHospitalofShengliPetroleumAdministrativeBureau,Dongying,ShandongProvince,257231,China[Abstract]ObjectiveTocomparetheclinicalefficacybetweenamiodaroneandcedilanidinthetreatmentofrapidparoxysmala-trialfibrilationwithintravenousadministrat4、ion.Methods92patientswithrapidparoxysmalatrialfibrillationwereselectedandrandomlydividedintoamiodaronegroup=46)andcedilanidgroup(n=46),andrespectivelytreatedwithamiodaroneandcedilanidintravenously.Theeffectiverate,changeofheartrateandadversereactionsofthetwogroupswer5、eobserved.ResultsThetotalef-fectiveratewas82.61%intheamiodaronegroupand58.70%inthecedilanidgroup,withasignificantdiferencebetweenthetwogroups0.05).TherewasstatisticallysignificantdifferenceinheartrateoftwogroupsofpatientsbeforeandafterthetreatmentcP.<0.05).Comparedwi6、ththecedilanidgroup,theeficacyofamiodaronegroupwasmoreobviousandthediferencebetweenthetwogroupswasstatisticallysignificantfP<0.05).ConclusionIntravenousamiodaroneismoreefectivethancedilanidforrapidparoxysmalartrialfibrillation,withminorsideefects.Itisworthyofclinical7、promotion.[Keywords]Atrialfibrillation;Amiodarone;Cedilanid心房纤颤是临床上常见的心律失常。多见于器质性心脏病。间质纤维化、急性心肌梗死、病态窦房结综合征、预激综合症以阵发性房颤,如频繁发作,可发展为慢性永久性房颤,发生脑栓及房室传导阻滞。将人选患者随机分为胺碘酮组、西地兰组各46塞的概率增加。如伴随快速心室率。可有明显症状及血流动力学例。胺碘酮组男22例,女24例,平均年龄(57.6~15.7)岁,平均血压(132.4~22.1/81.2~12-3)mmhg。西地兰组男8、21例,女25例,平异常,诱发心脑血管疾病【1]。故恢复窦性节律、降低心室率对于治均年龄(56.4~16-3)岁,平均血压(128.1~23.3/82.4~10.8)mmhg。疗快速阵发性房颤有着重要意义。该研究选取该院2009年1两组在患者年龄、性别、平均血压
2、(P<0.05)。结论静脉应用胺碘酮治疗快速阵发性房颤,疗效优于西地兰,不良反应轻,值得推广。【关键词】心房颤动;胺碘酮;西地兰【中图分类号】R4【文献标识码】A【文章编号】1674—0742(2014)07(b)一0008—02ComparisonoftheClinicalEficacyBetweenAmiodaroneandCedilanidintheTreatmentofRapidParoxysmalAtrialFibrillationthIntravenousAd·ministrationLIYonTheFirstDep
3、artmentofInternalMedicine,GudaoHospitalofShengliPetroleumAdministrativeBureau,Dongying,ShandongProvince,257231,China[Abstract]ObjectiveTocomparetheclinicalefficacybetweenamiodaroneandcedilanidinthetreatmentofrapidparoxysmala-trialfibrilationwithintravenousadministrat
4、ion.Methods92patientswithrapidparoxysmalatrialfibrillationwereselectedandrandomlydividedintoamiodaronegroup=46)andcedilanidgroup(n=46),andrespectivelytreatedwithamiodaroneandcedilanidintravenously.Theeffectiverate,changeofheartrateandadversereactionsofthetwogroupswer
5、eobserved.ResultsThetotalef-fectiveratewas82.61%intheamiodaronegroupand58.70%inthecedilanidgroup,withasignificantdiferencebetweenthetwogroups0.05).TherewasstatisticallysignificantdifferenceinheartrateoftwogroupsofpatientsbeforeandafterthetreatmentcP.<0.05).Comparedwi
6、ththecedilanidgroup,theeficacyofamiodaronegroupwasmoreobviousandthediferencebetweenthetwogroupswasstatisticallysignificantfP<0.05).ConclusionIntravenousamiodaroneismoreefectivethancedilanidforrapidparoxysmalartrialfibrillation,withminorsideefects.Itisworthyofclinical
7、promotion.[Keywords]Atrialfibrillation;Amiodarone;Cedilanid心房纤颤是临床上常见的心律失常。多见于器质性心脏病。间质纤维化、急性心肌梗死、病态窦房结综合征、预激综合症以阵发性房颤,如频繁发作,可发展为慢性永久性房颤,发生脑栓及房室传导阻滞。将人选患者随机分为胺碘酮组、西地兰组各46塞的概率增加。如伴随快速心室率。可有明显症状及血流动力学例。胺碘酮组男22例,女24例,平均年龄(57.6~15.7)岁,平均血压(132.4~22.1/81.2~12-3)mmhg。西地兰组男
8、21例,女25例,平异常,诱发心脑血管疾病【1]。故恢复窦性节律、降低心室率对于治均年龄(56.4~16-3)岁,平均血压(128.1~23.3/82.4~10.8)mmhg。疗快速阵发性房颤有着重要意义。该研究选取该院2009年1两组在患者年龄、性别、平均血压
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