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时间:2020-05-02
《右美托咪定对下肢手术腰麻后寒颤的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·768·临床麻醉学杂志2013年8月第29卷第8期JClinAnesthesiol,August2013,Vo1.29,No.8.临床研究.右美托咪定对下肢手术腰麻后寒颤的影响徐凯朱敏敏胡毅平【摘要】目的观察右美托咪定对下肢手术腰麻后寒颤的预防作用。方法择期下肢手术患者60例,随机均分为两组,麻醉前分别静脉滴注右美托咪定1ttg/kg(D组)或生理盐水100ml(C组)。选择~。或L。~间隙腰麻,0.5罗哌卡因10mg,控制麻醉平面在T。以下。记录用药前、用药后15、30min的MAP、HR和Sp()2,及术中寒颤的发生情况。结果与用药前及C组比较,用药
2、后15、30rain,D组MAP明显降低,HR明显减慢(Pd0.05),SpOz组问差异无统计学意义。D组术中有4例(13.3)患者发生寒颤,明显低于C组的12例(40.0)(P3、DepartmentofAnesthesiology,SecondPeople’SHospitaloff,Ⅵ,“214002.ChinaCorrespondingauthor:UKai,Emaif:XUkai一2290@163.corn[Abstract]ObjectiveToobservetheeffectofdexmedetomidineonpreventingshiveringinpatientsduringspinalanesthesia.MethodsSixtyASAIorⅡpatientsundergoingselectivelowerextr4、emityoperationunderspinalanesthesiawererandomlydividedintotwogroups(一30each).Patientswereintravenouslyinjecteddexmedetomidine1/~g/kg(dissolvedin100mlsaline,groupD)orsamevolumeofsaline(groupC)beforespinalanesthesia.Thechangesofvitalsignsafterinjection15,30rainwererecorded.Theoccurr5、enceofshiveringwasobserved.Theincidenceofadversereactionwasrecorded.ResultsMeanarterialpressure(MAP)andheartrate(HR)wereloweringroupDthaningroupCat15and30minafterinjection(P<0.05).Therewasnosignificantdifferenceinsaturationofoxygen(SpOz)betweenthetwogroups.GroupD(13.3)hadalowershi6、veringincidencethanthegroupC(40.0)(P<0.05).Therewasnosignificantdifferenceintheincidenceofadversereactionbetweenthetwogroups.ConclusionDexmedetomidinemaybeeffectiveinpreventingshiveringduringspinalanesthesia[Keywords]Dexmedetomidine;Spinalanesthesia;Shivering寒颤是腰麻后常见并发症,发生率可达40~麻醉7、方法患者人室后常规鼻导管吸氧,监测64。右美托咪定是一种高选择性a。肾上腺素HR、BP、SpOz,开放外周静脉通道。手术室温度设受体激动药,具有镇静、镇痛、抗焦虑、抑制交感活性在21~22℃,术中冲洗及静脉滴注的液体保存在室效应,且对呼吸影响轻微E。本研究观察右美托咪温条件下,均未加温处理。所有患者只盖一层小薄定对腰麻后寒颤的预防作用,为临床提供参考。被。在实施腰麻前,D组静脉滴注右美托咪定1g/kg(生理盐水100m1),C组静脉滴注生理盐水100资料与方法ml,滴注时间均为15min。用药结束后选择L~。或一般资料选择拟在腰麻下行择期下肢手术患L嵋~间8、隙实施腰麻,蛛网膜下腔注人0.5罗哌卡者6O例,ASA工或Ⅱ级,年
3、DepartmentofAnesthesiology,SecondPeople’SHospitaloff,Ⅵ,“214002.ChinaCorrespondingauthor:UKai,Emaif:XUkai一2290@163.corn[Abstract]ObjectiveToobservetheeffectofdexmedetomidineonpreventingshiveringinpatientsduringspinalanesthesia.MethodsSixtyASAIorⅡpatientsundergoingselectivelowerextr
4、emityoperationunderspinalanesthesiawererandomlydividedintotwogroups(一30each).Patientswereintravenouslyinjecteddexmedetomidine1/~g/kg(dissolvedin100mlsaline,groupD)orsamevolumeofsaline(groupC)beforespinalanesthesia.Thechangesofvitalsignsafterinjection15,30rainwererecorded.Theoccurr
5、enceofshiveringwasobserved.Theincidenceofadversereactionwasrecorded.ResultsMeanarterialpressure(MAP)andheartrate(HR)wereloweringroupDthaningroupCat15and30minafterinjection(P<0.05).Therewasnosignificantdifferenceinsaturationofoxygen(SpOz)betweenthetwogroups.GroupD(13.3)hadalowershi
6、veringincidencethanthegroupC(40.0)(P<0.05).Therewasnosignificantdifferenceintheincidenceofadversereactionbetweenthetwogroups.ConclusionDexmedetomidinemaybeeffectiveinpreventingshiveringduringspinalanesthesia[Keywords]Dexmedetomidine;Spinalanesthesia;Shivering寒颤是腰麻后常见并发症,发生率可达40~麻醉
7、方法患者人室后常规鼻导管吸氧,监测64。右美托咪定是一种高选择性a。肾上腺素HR、BP、SpOz,开放外周静脉通道。手术室温度设受体激动药,具有镇静、镇痛、抗焦虑、抑制交感活性在21~22℃,术中冲洗及静脉滴注的液体保存在室效应,且对呼吸影响轻微E。本研究观察右美托咪温条件下,均未加温处理。所有患者只盖一层小薄定对腰麻后寒颤的预防作用,为临床提供参考。被。在实施腰麻前,D组静脉滴注右美托咪定1g/kg(生理盐水100m1),C组静脉滴注生理盐水100资料与方法ml,滴注时间均为15min。用药结束后选择L~。或一般资料选择拟在腰麻下行择期下肢手术患L嵋~间
8、隙实施腰麻,蛛网膜下腔注人0.5罗哌卡者6O例,ASA工或Ⅱ级,年
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