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《右美托咪定对小儿全麻苏醒期的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、第22卷第3期China中Jo国ur现na代lo医fM学od杂ern志MedicineV0I.22No.32012年1月Jan.2012文章编号:1005-8982(2012)03-0082-03右美托咪定对dxJL全麻苏醒期的影响马孝武,张宜林,伍军,马亚飞,邢群智(河南科技大学第一附属医院麻醉科,河南洛阳471003)摘要:目的观察右美托咪定预防小儿全麻苏醒期躁动的效果。方法选择ASA分级I一Ⅱ级在丙泊酚复合瑞芬太尼静脉全麻行腹股沟疝行常规手术的患儿60例。随机分为对照组(c组)和右美托咪定(D组)组各30例,麻醉前对
2、照组注射生理盐水10mL,右美托咪定组注射右美托咪定O.5g/kg,两组患儿静脉注射瑞芬太尼O.5g/kg和丙泊酚2mg/kg麻醉诱导,麻醉维持采用静脉输注丙泊酚5mg/kg·h和瑞芬太尼O.2g/kg·min,在手术结束前15min静脉注射芬太尼0.1g/kg。记录小儿苏醒时(Tn)、小儿苏醒后10min(T,)、小儿苏醒后30min(T2)、小儿苏醒后60min(-T3)的FIlL、Sp0:。记录小儿苏醒时间、躁动评分及躁动例数。结果两组小儿苏醒后各时间点Sp0:比较无统计学意义,但苏醒后各时间点右美托咪定组患儿的HR
3、.比对照组低,比较具有统计学意义。D组比c组的苏醒时间延长,具有统计学意义。美托咪定组患儿躁动评分比对照组低,两组间比较有统计学意义,躁动例数D组比c组明显少比较,比较有统计学意义(P_4、lrenMAXiao-wu,ZHANGYi-lin,WUJu,MAYa-fei,XINGQun-zhi(DepartmentofAnaesthesia,theFirstAffiliatedHospitalofHenanUniversityofScienceandTechnology,Luoyang,Henan471003,P.R.China)Abstract:【objective】ToobservetheefectofDexmedetomidineonrecoveryofgeneralanesthesiainchildre5、n.【Methods】60childrenofASAfI-II)werescheduledtoroutineinguinalherniaduringgeneralanesthesia.Theywererandomlydividedtotwogroups:Thecontrolgroup(CU=30)andtheDexmedetomidinegroup(Dn=3o).ThepatientsofgroupCwereintravenouslyinfusednormalsaline10mlandthepatientsofgroupD6、wereintravenouslyinfusedDexmedetomidine0.5Ixg/kg.Allpatientswereintravenousinductionbyremifentanil0.5Ixg/kgandpropofol2mg/kg.Anesthesiawasmaintainedwithintravenousinfusionofpropofol5mg‘kg‘handremifentanil0.2Ixg/kg‘rain.Allpatientswereintravenousinfusedfentanil0.1I7、xg/kgat15minutesbeforetheendofsurgery.Heartrate(HR)plusoxygensaturatio(SpO2)nwereobservedandrecordedatwake—upafteranesthesia,10minafterwake-up(T1),30minafterwake-up㈣,60minafterwake-up(T3).Wake-uptime,thecasesofemergenceagitation,thescoreofemergenceagitationwereobs8、ervedandrecorded.【Results】TherewasnodiferenceonSpO2intwogroupsofchildren.TheHRingroupDwassignificantlylowerthanthatingroupC.Thewake-uptimeingroupDwassig
4、lrenMAXiao-wu,ZHANGYi-lin,WUJu,MAYa-fei,XINGQun-zhi(DepartmentofAnaesthesia,theFirstAffiliatedHospitalofHenanUniversityofScienceandTechnology,Luoyang,Henan471003,P.R.China)Abstract:【objective】ToobservetheefectofDexmedetomidineonrecoveryofgeneralanesthesiainchildre
5、n.【Methods】60childrenofASAfI-II)werescheduledtoroutineinguinalherniaduringgeneralanesthesia.Theywererandomlydividedtotwogroups:Thecontrolgroup(CU=30)andtheDexmedetomidinegroup(Dn=3o).ThepatientsofgroupCwereintravenouslyinfusednormalsaline10mlandthepatientsofgroupD
6、wereintravenouslyinfusedDexmedetomidine0.5Ixg/kg.Allpatientswereintravenousinductionbyremifentanil0.5Ixg/kgandpropofol2mg/kg.Anesthesiawasmaintainedwithintravenousinfusionofpropofol5mg‘kg‘handremifentanil0.2Ixg/kg‘rain.Allpatientswereintravenousinfusedfentanil0.1I
7、xg/kgat15minutesbeforetheendofsurgery.Heartrate(HR)plusoxygensaturatio(SpO2)nwereobservedandrecordedatwake—upafteranesthesia,10minafterwake-up(T1),30minafterwake-up㈣,60minafterwake-up(T3).Wake-uptime,thecasesofemergenceagitation,thescoreofemergenceagitationwereobs
8、ervedandrecorded.【Results】TherewasnodiferenceonSpO2intwogroupsofchildren.TheHRingroupDwassignificantlylowerthanthatingroupC.Thewake-uptimeingroupDwassig
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