右美托咪定对小儿全凭静脉麻醉苏醒期躁动的影响.pdf

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1、·2736·中华实验外科杂志2013年12月第3O卷第l2期ChinJExpSurg，December2013，Vo1．30，No．12·临床研究·右美托咪定对小儿全凭静脉麻醉苏醒期躁动的影响石念军张维霞张昊于海涛张宁王绪彩【摘要】目的观察右美托咪定预防小儿扁桃体腺样体切除术全凭静脉麻醉苏醒期躁动的作用。方法将60例全凭静脉麻醉下行择期扁桃体腺样体切除术患儿，随机分为实验组(A组)与对照组(B组)，诱导后分别持续静脉泵入右美托咪定每小时0．2kg和等容量的生理盐水至手术结束。记录患儿手术时间、停药至清醒

2、时间、恢复室滞留时间、到达恢复室t~IJN改良Aldrete评分、进入恢复室后30min内根据儿童麻醉后躁动评分(PAED)和改良加拿大东安大略儿童医院疼痛评分量表(m—CHEOPS)，每5min对患儿进行躁动和疼痛评分，所得最高值作为监测有效值。结果实验组与对照组比较，停药至清醒时间、Aldrete评分及恢复室滞留时间的差异无统计学意义(P>0．05)，PAED评分E组[(9．4±1．8)分]显著低于C组[(13．8±2．2)分，P<0．05]，疼痛评分E组[(3．8±0．6)分]显著低于C组[(4．

3、8±0．8)分，P<0．05]。结论右美托咪定可在一定程度上预防,'bJL扁桃体腺样体切除术全凭静脉麻醉苏醒期躁动的发生。【关键词】右美托咪定；全凭静脉麻醉；躁动Theefectsofdexmedetomidineonemergencedeliriaminpediatrieundertotalintravenousanesthe．siaSH／Nian-jun，ZHANGWei—xiazHANGHao。YUH8i—taozHANGNtng，WANGXu—cai．Depart—mentofAnesthesi

4、ology，LinyiPeople’sHospital，Linyi276003，ChinaCorrespondingauthor：zHANGHao。Emails晒l976@l63．corn【Abstract】ObjectiveToobservetheeffectsofdexmedetomidineonemergencedeliriuminpedi—atricadenotonsillectomyundertotalintravenousanesthesia(TIVA)．Methods60childrenu

5、ndergoingadenotonsillectomyunderTIVAwererandomlydividedintoexperimentalgroup(groupA)andcontrolgroup(groupB)．Anesthesiawasinducedthandexmedetomidinewasinfusedattherateof0．2kg．hingroupEandsodiumchloridewasinfusedatthesamevolumeingroupCafterinduction．Record

6、thetimeofoperation，drugwithdrawaltoconscious，retentiontimeofrecoveryroom，andthemodifiedAldretescoreofreachingrecoveryroom，accordingtothePediatricAnesthesiaEmergenceDeliriumtomarkthedeliriumofthepatientinthefuture30minutesper5minutes．thehighestscoreisused

7、toeffectivevalue．andatthesametime．markthedegreeofpainaccordingtothemodifiedChildren’sHospitalofEastern0ntarioPainScale．ResultsTherewasnostatisticaIsignificanceincomparationwithgroupCandgroupE．thetimeofdrugwithdrawaltoconscious，retentiontimeofrecoveryroom

8、．andthemodifiedAldretescoreofreachingrecoveryroom(P>0．05)．Pediatricanesthesiaemergencedelirium(PAE13)ofgroupE(9．4±1．8)wassignificantlylowerthangroupC(13．8±2．2)(P<0．05)，painofgroupE(3．8±0．6)wassignificantlylowerthangroupC(4