应用改良Simpson法评价肝豆状核变性患者胆囊收缩功能-论文.pdf

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1、·388·实用肝脏病杂志2014年7月第17卷箍4—JP—racHep—at—ol,Ju1．2014．Vo1．17No．4·肝豆状核变性·应用改良Simpson法评价肝豆状核变性患者胆囊收缩功能张靖，王金萍，王佳佳，伍宏兵【摘要】目的应用心脏左室容量计算法(改良Simpson法)评价肝豆状核变性患者胆囊收缩功能。方法选择肝豆状核变性患者54例和正常人60例，分别于空腹和脂餐试验后在胆囊长轴切面应用改良Simpson法测量胆囊容积，计算胆囊排空率。结果在空腹状态下，肝豆状核变性患者与正常对照组胆囊容积分别为(27．3

2、1±6．90)ml和(25．63±4．72)ml，差异无统计学意义(尸>0．05)；在高脂餐后，肝豆状核变性患者胆囊容积为(10．31±4．61)ml，明显大于正常对照组[(3．41±2．78)ml，P

3、son法DOI：10．39690．issn．1672—5069．2014．04．014ApplicationofthemodifiedSimpsonmethodinevaluationofgallbladdercontractilityinpatients、vithhepatolenticulardegenerationZhang，WangJinping，WangJiajic~GraduateSchool，AnhuiUnwemityofTra～ditiondlChineseMedwine，Hefei230031，A

4、nhuiProvince，China【Abstract】ObjectiveToevaluatethegallbladdercontractilityofpatientswithhepatolenticularde-generation(HLD)bycardiacleftventricularvolumecalculationmethod(modifiedSimpsonmethod)．MethodsThemodifiedSimpsonmethodwasconductedatthelongaxisviewtomeasu

5、rethegal1．—bladdervolumeof104subjects(54withHLDand60normalpersons)underfastingconditionsandaftertheadministrationoflipoid-food，andthegallbladderemptyingratesintwogroupswerecalculat-edandcompared．ResultsUnderthefastingstate．therewasnostatisticaldifferenceinthev

6、olumeofgallbladderbetweenthepatientswithHLD[(27．31±6．90)m1]andthehealthycontrols[(25．63±4．72)ml3；aftertheconductionoflipoid—foodtest，thegallbladdervolumeinpatientswithHLDwas(10．31±4．61)ml，significantlybiggerthaninthecontrols[(3．41±2．78)ml，P<0．05]，whilethegall—

7、bladderemptyingrateinpatientswithHLD[(54．85±12．12)％]wassignificantlylowerthanthatinthecontrols[(73．484-7．60)％，P<0．01]．ConclusionsThemodifiedSimpsonmethodiseasytoperformandofgoodrepeatabilityinmeasurementofgallbladdervolumeandishelpfulinevaluationofgall——bladde

8、rcontractilityinpatientswithHLD．【Keywords】Hepatolenticulardegeneration；Gallbladdercontractility；Ultrasound；Simpsonmethod肝豆状核变性(hepatolenticulardegeneration．Simpson法)观察了54例HLD患者和60例