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1、JournalofMedicalVirology29:238-243(1989)Coronavirus-LikeParticlesinAdultsinMelbourne,AustraliaJ.A.Marshall,W.L.Thompson,andI.D.GustVirologyDepartment,FairfieldHospital,Fairfield,Victoria,AustraliaCoronavirus-likeparticle(s)(CVLP)arefaecal-de-Thisstudyexaminesthequestionusingadultsi
2、nMel-rivedpleomorphicmembraneboundvirus-likebourne,Australia,asthetestpopulation.particlescharacterisedbyafringeofclub-MATERIALSANDMETHODSshapedspikesthatmeasureabout27nminlength.TheassociationofCVLPwithavarietyofMaterialssocial,clinical,andepidemiologicalfactorswasFairfieldInfecti
3、ousDiseasesHospitalisthechiefexaminedaftera69monthsurveyoffaecesre-centreforthediagnosisandmanagementofinfectiousceivedforroutinetestingataninfectiousdis-diseasesinthestateofVictoria,Australia,andassucheaseshospital.CVLPwasfoundmostcommonlyreceivesawiderangeofspecimensfromavarietyo
4、finthreegroups:first,intellectuallyretardedin-individuals.Duringthecourseofa69monthperioddividualswhowereusuallyinmatesofinstitu-fromJanuary,1980,toSeptember,1985,over2,000tions;second,recentoverseastravellerswhofaecalspecimensfromindividualsaged16yearsandwereeitherlndochineserefug
5、eeslimmigrantsoroverwereprocessedandexaminedbyelectronmicros-wereoverseastravellerswhohadusuallyvisitedcopy.Thesespecimenswerechieflyfrompatientswithdevelopingcommunitiesforlengthyperiods;ahistoryofgastroenteritis,althoughfaecalspecimensand,third,malehomosexualswhohadahistorywereal
6、soreceivedfromotherpatientsandhealthyper-ofmultiplesexualcontactsand/orvenerealdis-sonstemporarilyresidentinthehospital.ease.ItwasconcludedthattheexcretionofThisstudyisbasedonthe34casesfoundintheCVLPhadastrongassociationwithunhygieniccourseofthesurveywhenCVLPweredetectedandlivingor
7、workingconditionsirrespectiveofanydetailedrecordswereavailable.In26ofthesepatients,clinicalsymptomstheindividualmightshow.whicharereferredtoasgastroenteritiscases,diar-rhoeawasamajorsymptompriortoadmission.IntheKEYWORDS:hygiene,faeces,virus-likeparti-remainingeightcases,diarrhoeawa
8、seitherabsentorclesonlyami
