冠状病毒Coronavirusl论文-1985 Vaccination against enteric rota and coronaviruses in cattle and pigs_ Enhancement of lactogenic immunity.pdf

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1、ReviewVaccinationagainstentericrotaandcoronavirusesincattleandpigs:enhancementoflactogenicimmunityC.F.CrouchPathogenesisofinfectionPassiveimmunityagainstentericviralinfectionsisThepathogenesisofentericrotavirusandcoronavirusdependentuponthecontinualpresenceinthegutdiseases

2、ofswineandcattlearesimilar.IncontrasttolumenofaprotectivelevelofspecificTGEV,however,rotavirusesappeartobeconfinedtotheantibodies.Thisarticleexaminesmethodscurrentlyalimentarytract,predominantlythesmallintestine,usedtoenhancethetitreanddurationofspecificalthoughthereissome

3、evidenceinbothlambsandpigletsantibodyinthemammarysecretionsofcowsandforinfectionofthelargeintestinal9,2°.Theinfectionsarepigs~withparticularreferencetorotavirusandcharacterizedbydiarrhoeaanddehydrationcausedbycoronavirusinfections.Inaddition,someofthethefunctionalandanatom

4、icallossoftheabsorbtivecellspotentialproblemstobefoundinattemptingtooftheintestine.Theprincipalsiteofvirusreplicationhasproducevaccinesagainsttheseviralinfectionsbeenshowntobetheintestinalvillusepithelium.Theareoutlinedinfectedcellsarelostfromthetipsofthevilliandarereplace

5、dwithimmaturecryptcells.Generally,thereisadimunitioninthenumberandsizeofthevilliandaKeywords:Viruses:rotavlrus:coronavirus:cattle:pigslaclogenicprogressivereplacementoftheepitheliumwithsquamousimmunityandcuboidalcellswhichlackabrushbordeP-6.~.2°-26.Suchimmaturecellshavebee

6、nshowntopossessreducedlevelsofdisaccharidases=~.28.ThelossoftheabsorptiveIntroductioncellsoftheintestineisassumedtoresultintheobservedmalabsorptionsyndrome.ThisisfurtherexacerbatedbyNeonataldiarrhoeaisacomplexdiseaseassociatedwithathedecreasedabilitytoutilizedietarylactose

7、,resultinginnumberofinfectiousagentsoccurringeithersinglyorinitsaccumulationinthelargeintestine,therebypreventingcombination~-3.Indomesticanimalseconomiclossesarefurtherabsorptionofwaterbyexertinganosmoticsuffered,asaresultofmortality(rangingbetween0andeffect.80%),andalsov

8、eterinarycostsanddecreasedproductivityofthesurvivors.Theviralagentsmostcommonlyassociated