Early prediction of long-term upper limbspasticity after stroke长期上肢早期预测 脑卒中后痉挛状态

Early prediction of long-term upper limbspasticity after stroke长期上肢早期预测 脑卒中后痉挛状态

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时间:2019-08-08

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1、Earlypredictionoflong-termupperlimbspasticityafterstrokePartoftheSALGOTstudyArveOpheim,PT,PhDABSTRACTAnnaDanielsson,PT,Objective:ToidentifypredictorsandtheoptimaltimepointfortheearlypredictionofthepresencePhDandseverityofspasticityintheupperlimb12mon

2、thspoststroke.MargitAltMurphy,PT,Methods:Intotal,117patientsintheGothenburgareawhohadexperiencedastrokeforthefirstPhDtimeandwithdocumentedarmparesisday3poststrokewereconsecutivelyincluded.AssessmentsHannaC.Persson,PT,weremadeatadmissionandat3and10day

3、s,4weeks,and12monthspoststroke.UpperlimbMScspasticityinelbowflexion/extensionandwristflexion/extensionwasassessedwiththemodifiedKatharinaStibrantAshworthScale(MAS).AnyspasticitywasregardedasMAS$1,andseverespasticitywasre-Sunnerhagen,MD,gardedasMAS$2i

4、nanyofthemuscles.Sensorimotorfunction,sensation,pain,andjointrangePhDofmotionintheupperlimbwereassessedwiththeFugl-Meyerassessmentscale,and,togetherwithdemographicanddiagnosticinformation,wereincludedinbothunivariateandmultivariatelogisticregressiona

5、nalysismodels.Seventy-sixpatientswereincludedinthelogisticregressionanalysis.CorrespondencetoDr.Opheim:Results:Sensorimotorfunctionwasthemostimportantpredictorbothforanyandseverespastic-arve.opheim@neuro.gu.seity12monthspoststroke.Inaddition,spastici

6、ty4weekspoststrokewasasignificantpredictorforseverespasticity.Thebestpredictionmodelforanyspasticitywasobserved10dayspost-stroke(85%sensitivity,90%specificity).Thebestpredictionmodelforseverespasticitywasobserved4weekspoststroke(91%sensitivity,92%spe

7、cificity).Conclusions:Reducedsensorimotorfunctionwasthemostimportantpredictorbothforanyandseverespasticity,andspasticitycouldbepredictedwithhighsensitivityandspecificity10dayspoststroke.Neurology®2015;85:873–880GLOSSARYADL5activitiesofdailyliving;ARA

8、T5ActionResearchArmTest;CI5confidenceinterval;FMA-UE5Fugl-MeyerAssess-mentUpperExtremityScale;MAS5modifiedAshworthScale;NIHSS5NIHStrokeScale;NLR5negativelikelihoodratio;PLR5positivelikelihoodratio;ROM5rangeofmotion;SALGOT5StrokeArmLongitudinalStudyat

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