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1、Earlypredictionoflong-termupperlimbspasticityafterstrokePartoftheSALGOTstudyArveOpheim,PT,PhDABSTRACTAnnaDanielsson,PT,Objective:ToidentifypredictorsandtheoptimaltimepointfortheearlypredictionofthepresencePhDandseverityofspasticityintheupperlimb12mon
2、thspoststroke.MargitAltMurphy,PT,Methods:Intotal,117patientsintheGothenburgareawhohadexperiencedastrokeforthefirstPhDtimeandwithdocumentedarmparesisday3poststrokewereconsecutivelyincluded.AssessmentsHannaC.Persson,PT,weremadeatadmissionandat3and10day
3、s,4weeks,and12monthspoststroke.UpperlimbMScspasticityinelbowflexion/extensionandwristflexion/extensionwasassessedwiththemodifiedKatharinaStibrantAshworthScale(MAS).AnyspasticitywasregardedasMAS$1,andseverespasticitywasre-Sunnerhagen,MD,gardedasMAS$2i
4、nanyofthemuscles.Sensorimotorfunction,sensation,pain,andjointrangePhDofmotionintheupperlimbwereassessedwiththeFugl-Meyerassessmentscale,and,togetherwithdemographicanddiagnosticinformation,wereincludedinbothunivariateandmultivariatelogisticregressiona
5、nalysismodels.Seventy-sixpatientswereincludedinthelogisticregressionanalysis.CorrespondencetoDr.Opheim:Results:Sensorimotorfunctionwasthemostimportantpredictorbothforanyandseverespastic-arve.opheim@neuro.gu.seity12monthspoststroke.Inaddition,spastici
6、ty4weekspoststrokewasasignificantpredictorforseverespasticity.Thebestpredictionmodelforanyspasticitywasobserved10dayspost-stroke(85%sensitivity,90%specificity).Thebestpredictionmodelforseverespasticitywasobserved4weekspoststroke(91%sensitivity,92%spe
7、cificity).Conclusions:Reducedsensorimotorfunctionwasthemostimportantpredictorbothforanyandseverespasticity,andspasticitycouldbepredictedwithhighsensitivityandspecificity10dayspoststroke.Neurology®2015;85:873–880GLOSSARYADL5activitiesofdailyliving;ARA
8、T5ActionResearchArmTest;CI5confidenceinterval;FMA-UE5Fugl-MeyerAssess-mentUpperExtremityScale;MAS5modifiedAshworthScale;NIHSS5NIHStrokeScale;NLR5negativelikelihoodratio;PLR5positivelikelihoodratio;ROM5rangeofmotion;SALGOT5StrokeArmLongitudinalStudyat