左炔诺孕酮宫内缓释系统对子宫腺肌病疗效的临床观察

《左炔诺孕酮宫内缓释系统对子宫腺肌病疗效的临床观察》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、授予单位代码10089学号或申请号08010130014对於(E科走5HebeiMedicalUniversity硕士学位论文专业学位左炔诺孕酮宫内缓释系统对子宫腺肌病疗效的临床观察研究生：邱涵雅导师：王建英教授专业：妇产科学二级学院：第四医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研宄所获的研宄成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名单位为河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所

2、有。否则，承担相应的法律责任。研究生签名^导师签章：二级学院领导莾章:#fS年2月占I曰河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研宄工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名：々级;•导师签章：士(，多月〒目录中文摘要·················································································1英文摘要····························

3、·····················································3英文缩写·················································································6研究论文左炔诺孕酮宫内缓释系统对子宫腺肌病疗效的临床观察前言·················································································7材料与方法·······································

4、·································7结果·················································································9附表···············································································12讨论···············································································16结论··········

5、·····································································22参考文献·········································································22综述左炔诺孕酮宫内缓释系统的临床应用··································27致谢·····················································································37个人简

6、历···············································································38中文摘要左炔诺孕酮宫内缓释系统对子宫腺肌病疗效的临床观察摘要目的：子宫腺肌病是妇科的常见疾病。近年来发病率呈上升趋势，且发病人群逐渐趋于年轻化。子宫腺肌病的临床表现主要为继发性痛经呈进行性加重，可伴月经过多，已严重影响育龄妇女生活质量。药物治疗有假绝经疗法和假孕疗法，均可使子宫内膜萎缩，改善症状。但是药物治疗存在较多副反应，患者往往难以坚持使用，依从性较差。因此患者在药物治疗无效情况下多进行子宫切除术。手术治疗虽然疗效显著，

7、但是亦存在相应的手术风险及卵巢血供减少进而影响卵巢功能等并发症。故此选择一种既副作用少又创伤小的治疗方法变得十分重要。左炔诺孕酮宫内缓释系统（Levonorgestrel-releasingintrauterinesystem，LNG-IUS，商品名：曼月乐）可以在5年的有效期内向宫腔恒定地释放左炔诺孕酮(levonorgestrel，LNG)，对子宫腺肌病有持续治疗的作用。本文对曼月乐治疗子宫腺肌病的疗效、不良反应及满意度方面进行观察研究，以