脊柱转移瘤经皮椎体成形术疗效的mri评价

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1、硕士学位论文论文题目脊柱转移瘤经皮椎体成形术疗效的MRI评价易飞研究生姓名指导教师姓名吴春根专业名称影像医学与核医学研究方向骨关节介入放射学论文提交日期2013年5月脊柱转移瘤经皮椎体成形术疗效的MRI评价中文摘要脊柱转移瘤经皮椎体成形术疗效的MRI评价中文摘要目的:判断MRI检查结果能否为临床脊柱转移瘤患者经皮椎体成形术（PVP）术后疗效提供可靠的客观评价。方法:本文回顾性分析36例患者共75节椎体转移瘤采用单纯PVP治疗的临床及医学影像学检查资料。术前及术后进行视觉模拟疼痛评分（VAS）。根据MRI检查显示分为三组：病灶完全消失并持续12周为完全缓解(A组)；病灶出现骨化或肿瘤体积缩

2、小,无新转移灶出现并连续保持12周为部分缓解（B组）；通过测量肿瘤体积反映病灶扩大,表示无效（C组）。然后比较3组术前、术后12周疼痛缓解程度。结果:3组间术前VAS差异无统计学意义（P>0.05），术后C组疼痛缓解不明显，A组比B组疼痛缓解程度大，疼痛缓解程度差异有统计学意义（P<0.05）。表明MRI客观检查结果与临床主观评价一致。结论:PVP是治疗脊柱转移瘤的有效方法，MRI检查能为临床脊柱转移瘤患者PVP术后疗效提供可靠的客观评价。【关键词】:脊柱转移瘤；磁共振成像；经皮椎体成形术作者：易飞指导教师：吴春根I英文摘要脊柱转移瘤经皮椎体成形术疗效的MRI评价MRIEVALUATIO

3、NOFPERCUTANEOUSVERTEBROPLASTYFORSPINALMETASTASESAbstractObjective:ThemainpurposeofthisarticleistodeterminewhetherMRIfindingscanprovidereliableandobjectiveevaluationofpercutaneousvertebroplasty(PVP)intreatingspinalmetastases.Methods:PVPprocedureswerecarriedoutinatotalof36consecutivepatientswith75v

4、ertebralmetastases．Theclinicaldataandtheimagingmaterialswereretrospectiveanalyzed．Visualanalogscale(VAS)wasdeterminedbeforeandafterthetreatment.AccordingtoMRIfindingsonsagittalscans，thepatientsweredividedintothreegroups.GroupA(completeremissiongroup):thelesionscompletelydisappearedfor12weeks.Grou

5、pB(partialremissiongroup):thelesionsdevelopedossificationorthetumor’svolumedecreased,nonewmetastasesappeared,andtheconditionmaintainedfor12consecutiveweeks.GroupC(unresponsivegroup):thetumor’svolumebecamelarger．Byusingindependent-samplest-testandpaired-samplest-testanalysis，thepreoperativeandpost

6、operativeVASvalueswerecomparedamongthreegroups．Results:BeforePVPnosignificantdifferencesinVASexistedamongthreegroups(P>0.05).AfterPVPthedifferencesinVASamongthethreegroupswerestatisticallysignificant（P<0.05）.TheextentofpainreliefingroupCwasnotveryobvious,whilethedegreeofpainreliefingroupAwasmorep

7、rominentthanthatingroupB（P<0．05）,indicatingthatobjectiveMRIfindingswereinaccordancewiththepatient’ssubjectiveassessment.Conclusion:PVPisaneffectivetreatmentforspinalmetastases.MRIresultscanprovidereliableandobjectiveev