脑干听觉诱发电位

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1、BrainstemAuditoryEvokedPotentials(BAEP)R林岱樓/V.S.黃啟原Date:2013.08.09www.company.comIntroduction•AuditoryEvokedPotentials(AEP)hasbeendividedto3typeasshort-latency(~10ms),intermediate,andlong-latency.•Auditorybrainstemresponse(ABR)isaneurologictestofauditorybrainstemfunction.FirstdescribedbyJewettan

2、dWillistonin1971ClickortoneburstVertexForeheadAc;McAiMihttp://drugline.org/img/term/brainstem-auditory-evoked-potentials-2156_0.jpgwww.company.comStimulation•Clickstimuli:–monophasicsquarepulseof100-μsecduration–Rate:10Hz–Frequencyofclick:broad-band,widefrequencyrange•Intensity:60-65dB–Increased

3、ifhearinglossispresent–Loudenoughwithoutdiscomfort•Stimulicanreachtheotherearviaairandboneconductionwithvolumeattenuation(40~70dB)andgeneratetheevokedpotentialofcontra-lateralear–Ifnonoisemasking,thedelayedVwavewasnoted–Ifmasking(30~40dB),noelicitanyreproducibleBAEPs•Compressionclick;Rarefaction

4、clickwww.company.comRecording•Recordingelectrodes:vertex(Cz)andbothearlobesormastoid(smallerwaveI);groundforehead•Impedance:5kΩsorless(alsoequalbetweenelectrodes)•Avoidneedleelectrodes•Atypicalanalogfilterbandpass:100or150to3000Hz•Aepochduration:10.24msec•Theanalog-to-digitalconversionshoulduse

5、atleast256pointsperepoch,samplinginterval0.4msec,samplingrateof25000Hz•Thenumberofepochspertrialistypically2000,althoughalargernumbermayberequiredifthepoorsingaltonoiseratiowww.company.comHandbookofclinicalaudiology6thedition,Katz,2009www.company.comPhysiology•ABRtypicallyusesaclickstimulusthatg

6、eneratesaresponsefromthebasilarregionofthecochlea.•Thesignaltravelsalongtheauditorypathwayfromthecochlearnuclearcomplexproximallytotheinferiorcolliculus.•ABRwavesIandIIcorrespondtotrueactionpotentials.•Laterwavesmayreflectpostsynapticactivityinmajorbrainstemauditorycenters•IntheU.S.,waveI,III,an

7、dVarepositivepeaks.Inothercountries,thewavesareplottedwithanegativevoltage.www.company.comVI,VIIVIVIIII,IIhttp://www.docstoc.com/docs/126098489/The-Auditory-Nervous-System---PowerPointwww.company.comWaveformcomponents•WaveI: