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1、丙泊酚复合瑞芬太尼靶控输注在产科患者全身麻醉中的临床应用研究匮学理论与甄珪2011年第24卷第15期Vo1.24,No.15,Aug叟!壁!壁.r里!一团1773丙泊酚复合瑞芬太尼靶控输注在产科患者全身麻醉中的临床应用研究鲜澈艳四川省绵阳市妇幼保健院麻醉科621000摘要冃的:探讨丙泊酚复合瑞芬太尼靶控输注(targetcontrolledinfusions,TCI)在产科患者全身麻醉中的应用价值及安全性评价•方法t46例均选自2008-2010年我院麻醉科行全麻手术产科者，采用丙泊酚复合瑞芬太
2、尼麻醉诱导，气管插管后行机械通气，维持麻醉用微量泵持续输注瑞芬太尼，丙泊酚,派库漠桜，监测并记录患者诱导前，诱导后lOmin,手术开始时，术中30min,术毕的血压(SBP/DBP),心率(HR),Sp()z,苏醒时间及术后疼痛情况，观察整个手术过程不良反应•结果•诱导lOmin时HR较诱导前明显下降.差异有统计学意义(P<O.05)}SBlP/DBP诱导后lOmin开始下降，手术开始时未继续下降,术中及术毕血压平稳.2例患者术中30min时血压下降明显，予以输血补液后好转.所有患者Sp0
3、2均>96,术后苏醒吋间(24士8.66)min,术中未发生躁动,谄妄和呼吸抑制等不良反应.结论:丙泊酚复合瑞芬太尼靶控维持在全身麻醉中，对产科患者循环影响小，不良反应少，安全性较高.关键词丙泊酚瑞芬太尼靶控输注全身麻醉中图分类号:R971.2文献标识码:A文章编号:lo01—7585(2011)15—1773-02ApplicationofPropofoiandRemifentanilTarget-controlledlnfmionforGeneralAnesthesiainObstet
4、ricsPatientsXIANLianyan.DepartmentofAnesthesiology,MaternalandChildCareServiceCenterofMianyangCity,SichuanProvince621000ABSIRACTObjective:TOinvestigatetheeffectofdisoprofoltargetcontrolledinfusionforgeneralanesthesiainobstet-ticspatients.Methods:46ca
5、sesinourdepartmentweretreatedbyreapropofolandremifentaniltargetcontrolledinfu一sion,anesthesiawasinducedthpinerocuronium,propofolandremifentanilandthenthepatientsweremechanicallyventilatedaltertrachealintubation,andanesthesiawasmaintainedbypumpingprop
6、ofbl,pinerocuroniumandremifen-tanil.Monitoringandrecordingbloodpressure,heartrate,oxygensaturationbeforeinduction,after1Omin.beginningofoperationJntraoperative30rainandendofoperation,recoverytimeandpostoperativepain.Observedsideeffectsduringtheentire
7、procedure.Results:HeartratewassignificantlydecreasedcomparedwithinductionafterlOmin.thedifferencewasstatisticallysignifieant(P<O.05).SBP/DBPdeclinedafterinduction1Omin,butitdidnotcontinuetodeclinebe-ginningofoperation.Bloodpressurewasstableaftersu
8、rgery.Thebloodpressuresignificantlydecreasedintwopa・tientsJtwasimprovedafterbloodtransfusiomOxygensaturationofallpatientswereabove96.Thepostoperativerecoverytimewas(24土8.66)min,Therewasnoagitation,deliriumandrespiratorydepressionandotheradversereacti
