甲胎蛋白检测对原发性肝癌诊治的作用

《甲胎蛋白检测对原发性肝癌诊治的作用》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、甲胎蛋白检测对原发性肝癌诊治的作用长沙市第四医院核医学科410006摘要：目的：观察原发性肝癌患者的甲胎蛋白变化，分析对比其结果的意义，并探讨甲胎蛋白检测对原发性肝癌诊治的作用。方法：对木院174例原发性肝癌患者、良性肝病患者和同期健康者进行甲胎蛋白检测，其中原发性肝癌患者共63例、良性肝病患者共59例作为实验组，同期健康者共52例作为对照组，同时对各组进行甲胎蛋白检测结果分析，评价甲胎蛋白检测在诊治原发性肝癌的临床价值。结果.•在63例原发性肝癌患者中，甲胎蛋白检测浓度是(331.7±80.3)ng/ml,良性

2、肝病患者的甲胎蛋白检测浓度是(36.9±12.7)ng/ml，正常健康者的甲胎蛋白检测浓度是(5.3±2.1)ng/ml,差异有统计学意义(P<0.05)。结论：在原发性肝癌诊断中，甲胎蛋白检测结果发挥重要作用，甲胎蛋白检测对原发性肝癌诊治只有更重要的临床价值。关键词：原发性肝癌；甲胎蛋白；诊断治疗[Abstract]Objective：Observetheeffectsofthalidomidetreatmentofelderlypatientsandrelapsedmultiplemyeloma

3、clinicalefficacyandeffectivenessandsafety,andtoexplorethemosteffectivemechanismforthetreatmentofsenilerelapsedmultiplemyeloma.Method：clinicalobservationon13casesofprimarytreatmentand12patientsabove60yearsofagewithrecurrentelderlymyelomapatients,weremadeofarsenictrio

4、xidecombinedwiththalidomidetreatment，intravenousarsenictrioxideforlOmg/dwhich，atthesametime,thecontinuousinjection28days,orallowdosethalidomide100200mmg/d，accordingtotheactualsituationofpatientsmaybeappropriatetoincrease，themaximumthelimitis300mg/d，28daysforacourseo

5、ftreatment，takingtwocoursesoftreatment，efficacyandsideeffectswereobservedduringtheevaluationofcurativeeffect,inaccordancewiththestandardEBMTeffect,accordingtotheNCICTCAECTCAE(NationalCancerInstituteCommonTerminologyCriteriaforAdverseEvents，version3)standardtoevaluat

6、etheadversereaction.Result：inthe13patientsnewlydiagnosed5casesofpartialremission(38.46%)，5casesofprogress(38.46%),and3casesineffective(23.08%).ln12casesofsenilemultiplemyelomapatients,4casesofpartialremission(33.3%),5cases(41%)hadimprovement，3cases(25%)areinvalid,th

7、etotaleffectiveratewas74.3%.Observedthat,inthetreatmentofcommonadversereactionsarenauseaandfatigue，abdominaldistensionandconstipation,skinrash,liverinjury,neutropenia,butaftertreatmentwillimprove.Conclusion：Arsenictrioxidethalidomideforthetreatmentofsenilerelapsedmu

8、ltiplemyelomaissafeandeffective，worthyofpromotion.【Keywords】Arsenictrioxide；Thalidomide；Elderlyandrelapsedmultiplemyeloma原发性肝癌是常见的恶性肿瘤之一，死