消癌平注射液联合放化疗在局部中晚期鼻咽癌治疗中的疗效观察

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1、消癌平注射液联合放化疗在局部中晚期鼻咽癌治疗中的疗效观察【摘要】日的：观察消癌平注射液联合诱导化疗及同步放化疗在局部中晩期鼻咽癌治疗中的疗效观察。方法：选収局部中晩期鼻咽癌患者60例，按随机数字表法分为治疗组（消癌平组联合放化疗组）30例和对照组（单纯放化疗组）30例，两组治疗前均未行过化疗、放疗、免疫治疗及中医屮药治疗等。观察治疗结束后两组肿瘤病灶变化情况、皮肤及口腔黏膜反应、骨髓抑制程度和肝肾功能情况。结果：治疗结束12个月后复查，治疗组完全缓解率高于对照组，差异有统计学意义（P〈0・05）；且

2、骨髓抑制较对照组轻（P〈0・05）,其他毒副评价相当。结论：消癌平注射液联合放化疗治疗中晚期鼻咽癌具有增效、减毒作用，值得进一步研究证实。【关键词】消癌平注射液；鼻咽癌；诱导化疗；同步放化疗ClinicalObservationofXiaoaipingCombinedwithRadiationandChemotherapyinTreatmentofNasopharyngealCarcinoma（NPC）/XIAOHong-mei,ZOUYan,WUXiao~liang.//MedicalInnova

3、tionofChina,2014,11（28）：051-053[Abstract】Objective：ToobservetheoutcomeofcombiningXiaoaipinginjectiontreatmentwithinducingchemotherapyandconcurrentchemoradiotherapyonlocallyadvancednasopharyngeedcancer・Method：60patientswithnasopharyngealcarcinoma(NPC)we

4、reselect,thepatientswererandomlydividedintotwogroups：onegroupof30patientsweretreatedwithXiaoaipingcombinedwithinducingchemotherapyandconcurrentchemoradiotherapy(thetreatmentgroup),andtheothergroupof30patientswastreatedsolelywithinducingchemotherapyandc

5、oncurrentchemoradiotherapy(thecontrolgroup)•Thetwogroupsbeforetreatmenthadnotbeendonechemotherapy,radiationtherapy,immunotherapyandChinesemedicinetroatmont,etc.Thechangosofthetumoraftertreatment,thereactionofskinandmucousmembraneofmouth,bonemarrowinhib

6、itiondegree,liverandkidneyfunctionwereobserved・Result：Checkedover12monthsaftertreatment,completeresponserateofthetreatmentgroupwashigherthanthecontrolgroup,thedifferencewasstatisticallysignificant(P<0.05),bonemarrowsuppressionwas1ighterthanthecontrolgr

7、oup(P<0.05),theothersideevaluationwerefairly.Conclusion：Xiaoaipingunitesradiationandchemotherapycanincreasethecurativeeffectoflocallyadvancednasopharyngealcarcinoma,toreducetheadversereaction.【Keywords]Xiaoaipinginjection；Nasopharyngealcarcinoma；Tnduct

8、ionchemotherapy；ChemoradiationFirst-authorsaddress：ZunyiMedicalCollegeAffiliatedTumorHospital,Zunyi563000,Chinadoi：10.3969/j.issrt1674-4985.2014.28.018鼻咽癌是头颈部常见的恶性肿瘤之一，放射治疗是其主要治疗方法。但因鼻咽癌症状缺乏典型性容易与其他良性病变混淆，故很多患者确诊时已属局部晚期，这类患者大多数需行诱导化疗联合同