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1、重症急性胰腺炎早期低白蛋白血症的临床研究论文薛平,黄宗文,李永红,郭佳,王忠朝,赵健蕾,游真【关键词】急性胰腺炎[摘要]目的:探讨重症急性胰腺炎(severeacutepancreatitis,SAP)早期低白蛋白血症的发生机制和临床特点,及其对预后的影响和防治措施。方法:2003年8月1日~2004年12月31日收治的SAP早期并发低白蛋白血症患者138例.freelinemiainearlystageABSTRACTObjective:Toinvestigatetheoccurringmechanismandclinicalch
2、aracteristicsofsevereacutepancreatitis(SAP)associatedinemiainearlystageanditsinfluenceonprognosisofSAPandthepreventiveandtherapeuticmanagementofthisdisease.Methods:OnehundredandthirtyeightcasesdiagnosedasSAPplicatedbyhypoalbuminemiainearlystageAugust1,2003toDecember31,
3、2004,andtheyaalbumin:mildhypoalbuminemia(30to35g/L)groupandseverehypoalbuminemia(30g/L)group.Theplicationsintheearlystage,relatedparameters,andtheincidencerateofinfectionandmortalityinthelaterstageorrhage,thescoreofacutephysiologyandchronichealthevaluationⅡ(APACHEⅡ)and
4、thefrequenciesofpulseandbreathintheseverehypoalbuminemiagroupildhypoalbuminemiagroup(P<0.05orP<0.01).ThedifferencesofincidencerateofhepaticfailureandthescoresofRansonandBalthazarCTbetortalityintheseverehypoalbuminemiagroupildhypoalbuminemiagroup(P<0.01)inthelaterstageo
5、fSAP.Conclusion:HypoalbuminemiaintheearlystagecanacceleratethedeteriorationinpathophysiologyofSAP.Theloaalbuminisintheearlystage,themoreplicationsandthehigherincidencerateofinfectionandmortalityicinflammatoryresponsesyndrome(SIRS)andabundantsupplementofalbumin,.freelin
6、oacidandlipidintimemaybecrucialtopreventtheoccurrenceanddeteriorationofhypoalbuminemia.KEY,BassiC,etal.Guidelinesforthemanagementofacutepancreatitis[J].JGastroenterolHepatol,2002,17(Suppl):S1539.3MizuguchiT,MukaiyaM,ImaizumiH,etal.Successfulmanagementofsevereacutepancr
7、eatitisultipleorganfailure[J].Pancreas,2004,28(2):211213.4严燕国,艾中立,刘志苏,等.当归注射液对重症急性胰腺炎胰肾损害的保护作用[J].肝胆胰外科杂志,2000,12(2):8789.