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时间:2020-04-23
《大黄联合早期空肠营养治疗重症急性胰腺炎的临床研究-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、重庆医科大学学报2014年第39卷第1期(JournalofChongqingMedicalUniversity2014.VOI.39No.1】一61一稻傣番馨究DOI:10.13406~.enki.cyxb.2014.01.015大黄联合早期空肠营养治疗重症急性胰腺炎的临床研究万兵,符海燕,尹江涛,张德厚(江苏大学附属医院1.ICU;2.普外科,镇江212001)【摘要】目的:观察大黄联合早期肠内营养对重症急性胰腺炎(severeacutepancreatitis,SAP)的疗效及探讨可能的作用机制。方法:74例SAP患者随机分成3组:全肠外营养组(totalpa
2、renteralnutrition,TPN)、早期肠内营养组(earlyenteralnutrition,EEN)及大黄联合早期肠内营养组(rhubarbwithEEN,Rhubarb)。入院后第1⋯3714天检测血白细胞介素一18(interleukin一18,IL一18),C反应蛋白(C—reactiveprotein,CRP)和淀粉酶(amylase,AMY)并记录APACHEⅡ评分;记录腹痛缓解时间、肠鸣音恢复时间、体温恢复时间、ICU住院日及平均住院日。结果:3组相比,Rhubarb组腹痛缓解时间最短、肠鸣音恢复最快、体温恢复时间最快、ICU住院日和平均住
3、院日更短,有统计学差异(P4、2—05—03RhubarbcombinedwithearlyenteralnutritioninthetreatmentofsevereacutepanCreat⋯SWanBinf,FuHaiyan。,YinJiangtao1,ZhangDehou(.DepartmentofIntensiveCareUnit;2.DepartmentofGeneralSurgery,theAffiliatedHospital,JiangsuUniversity)【Abstract]Objective:ToobservetheefficacyofRhubarbcombinedwit5、hearlyenteralnutritioninthetreatmentofsevereacutepan—creatitis(SAP).Methods:Totally74patientswithSAPwereadmittedtointensivecareunit(ICU)andwererandomlydividedinto3groups:Rhubarbwithearlyentneralnutritiongroup(Rhubarbgroup),totalparenteralnutritiongroup(TPNgroup)andearlyenteralnutrition6、group(EENgroup).Atthe1st,3rd,7thdandthe14thdafteradmission,seruminterleukin-18(IL-18),C-reactiveprotein(CRP)andserumamylase(AMY)weredetected;APACHEIIscoreswererecordedandlengthofabdominalpain,recoverytimeofbowelsoundsandbodytemperature,len~hofstayinICU,averagelengthofstaywereobserved.R7、esuluts:Thelengthofabdominalpain,recoverytimeofbowelsoundsandbodytemperature,lengthofstayinICUandaveragelen~hofstayweresignificantlyshorterinRhubarbgroupcomparedwiththoseintheothergroups(P<0.05).Atthe3thd,levelofserumCRPwasobviouslylowerinRhubarbgroupthaninTPNgroup(P<0.05);atthe7thd,
4、2—05—03RhubarbcombinedwithearlyenteralnutritioninthetreatmentofsevereacutepanCreat⋯SWanBinf,FuHaiyan。,YinJiangtao1,ZhangDehou(.DepartmentofIntensiveCareUnit;2.DepartmentofGeneralSurgery,theAffiliatedHospital,JiangsuUniversity)【Abstract]Objective:ToobservetheefficacyofRhubarbcombinedwit
5、hearlyenteralnutritioninthetreatmentofsevereacutepan—creatitis(SAP).Methods:Totally74patientswithSAPwereadmittedtointensivecareunit(ICU)andwererandomlydividedinto3groups:Rhubarbwithearlyentneralnutritiongroup(Rhubarbgroup),totalparenteralnutritiongroup(TPNgroup)andearlyenteralnutrition
6、group(EENgroup).Atthe1st,3rd,7thdandthe14thdafteradmission,seruminterleukin-18(IL-18),C-reactiveprotein(CRP)andserumamylase(AMY)weredetected;APACHEIIscoreswererecordedandlengthofabdominalpain,recoverytimeofbowelsoundsandbodytemperature,len~hofstayinICU,averagelengthofstaywereobserved.R
7、esuluts:Thelengthofabdominalpain,recoverytimeofbowelsoundsandbodytemperature,lengthofstayinICUandaveragelen~hofstayweresignificantlyshorterinRhubarbgroupcomparedwiththoseintheothergroups(P<0.05).Atthe3thd,levelofserumCRPwasobviouslylowerinRhubarbgroupthaninTPNgroup(P<0.05);atthe7thd,
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