肠道菌群通过胆碱能抗炎通路对脓毒症相关性脑病的作用及机制研究

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1、授予单位代码10089学号或申请号20150031中国图书分类号R459.9HebeiMedicalUniversity博士学位论文专业学位肠道菌群通过胆碱能抗炎通路对脓毒症相关性脑病的作用及机制研究研究生：李素彦导师：李中信教授李建国教授专业：外科学二级学院：河北医科大学第四医院·2018年3月目录中文摘要·································································1英文摘要·································

2、··························································4英文缩写····································································································11研究论文肠道菌群通过胆碱能抗炎通路对脓毒症相关性脑病的作用及机制研究引言·························································

3、·······························13第一部分脓毒症患者及大鼠的肠道菌群特征及其对脑功能的影响前言········································································14材料与方法···································································33结果·············································

4、·····················································36附图··································································································43附表·····················································································45讨论··········

5、···········································································46小结·····································································································47参考文献········································································

6、·······················49第二部分肠道菌群通过胆碱能抗炎通路影响脓毒症相关性脑病的发生前言··································································································50材料与方法······················································································60结果······

7、·····························································································62附图····································································································71附表·························································

8、·······································73讨论·······························································································75小结····················································