不同体重指数对右美托咪定辅助椎管内麻醉在老年患者中的影响

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1、授予单位代码10089学号或申请号16133中国图书分类号R614HebeiMedicalUniversity硕士学位论文学术学位不同体重指数对右美托咪定辅助椎管内麻醉在老年患者中的影响研究生：安爱荣1导师：康荣田教授专业：麻醉学二级学院：河北医科大学第二医院2018年3月目录中文摘要····························································································1英文摘要···················································

2、·········································3英文缩写····························································································5研究论文不同体重指数对右美托咪定辅助椎管内麻醉在老年患者中的影响前言····························································································6材料与方法····················

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5、··································································25综述右美托咪定辅助椎管内麻醉在老年下肢骨折手术中的应用·········28致谢····························································································38个人简历·····················································································

6、·······39中文摘要带格式的:段落间距段后:4磅,边框:底端:(无框线)不同体重指数对右美托咪定辅助椎管内麻醉在老年患者中的影响摘要目的：研究不同体重指数对右美托咪定辅助椎管内麻醉对老年患者的影响。方法：在老年患者行下肢骨折手术时应用序贯法测定右美托咪定用于不同体重指数患者的半数有效剂量。选择我院2017年1月~2017年12月行下肢骨折手术治疗的老年患者45例，年龄65-80岁，ASA分级II级或III级，无椎管内麻醉禁忌症。根据患者体重指数分为3组：I组体重指数≤18.5kg/m2，II组体重指数18.5~24kg/m2，III组体重指数≥24kg/m2。所有患者均

7、未用术前药，入室后开放上肢静脉通道，输注乳酸钠林格以10ml·kg-1·h-1输注，常规面罩吸氧，监测生命体征：血压、心率、脉搏血氧饱和度、呼吸频率、脑电双频指数。所有患者均选择L3-4间隙实施腰硬联合阻滞麻醉，蛛网膜下腔给予药物3ml(0.75%布比卡因2ml+10%葡萄糖1ml)，调整麻醉平面至T9-11水平，待平面固定、麻醉效果满意之后，3组患者均按照相同负荷剂量0.5ug·kg-1泵注右美托咪定15min。随后各组患者右美托咪定泵注速度采用序贯法给予：当前患者右美托咪定的泵注速度由上一患者的镇静