多时相ct血管成像与缺血性卒中临床的应用进展

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1、授予单位代码10089学号或申请号20153355中国图书分类号R743.3HebeiMedicalUniversity硕士学位论文专业学位多时相CT血管成像与缺血性卒中临床的应用进展研究生：赵丹萍导师：刘俊艳教授专业：神经病学二级学院：第三医院2018年3月目录中文摘要··············································································································1英文摘要·················

2、·····························································································2英文缩写··············································································································3综述多时相CT血管成像与缺血性卒中临床的应用进展···························6致谢·····

3、··············································································································24个人简历············································································································25中文摘要多时相CT血管成像与缺血性卒中临床的应用进展摘要多时相CT血管成像（Mult

4、iphaseCTAngiography，mCTA)是一种新型检查技术，它可以提供动脉峰值期、静脉峰值期、静脉晚期三个不同时期的软脑膜动脉的图像，利用其与时间的相关性，可以评估颅脑的血管通路如二级侧支循环的存在；通过不同时相血流清除程度评估病变局部静脉压力；利用不同时期血管通透性的变化评估出血转化风险；测量血栓长度及评估血栓渗透性，评估血栓性质。利于侧支循环评估，指导血管内治疗方案的选择以及血管再通率、出血转化风险，评估临床预后等。本综述阐述了mCTA的时间相关性原理，解读了mCTA对二级侧支循环的评价方法，阐述了“斑点征”与血管通

5、透性改变的相关性，阐述了血栓性质和血栓长度的识别。该综述将有助于临床医生掌握血管影像学的使用，利于缺血性卒中急性期（AcuteIschemicStroke,AIS）诊疗措施的选择和卒中患者预后的评估。关键词：多时相CT血管成像，时间相关性，二级侧支循环，血管通透性，血栓性状，急性缺血性卒中1英文摘要TheAdvancedResearchofMultiphaseCTAngiographyAndIt’sClinicalApplicationInAcuteIschemicStrokeABSTRACTMultiphaseCTAngiogr

6、aphy(mCTA),asanewimagingtechnology,couldprovidethree-phasesvesselimages,andhavethepropertyoftime-resolved,thesephaseswerepeakarterialphase,peakvenousphaseandlatevenousphase.Itwasusedtoevaluatevascular-accessproblems,suchasthesecondarycollateralcirculations.Italsocould

7、assesscerebralvenouspressureviatheextendofcontrastwashout,andevaluatehemorrhagictransformationviachangesofvascularpermeability,aswellasmeasurethethrombustraitssuchaslengthandperviousnessofthrombus.Clinically,usingmCTAtoevaluatesecondarycollateralcirculationscanhelpeva

8、luatebraintissueperfusion,makeprotocolsofendovasculartreatments.Itcanguidedoctorstoassesstherevascularizationratio,hazardofh