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1、腰椎峡部裂病理模型的建立和疲劳特性的研究张志王簕吕玉明张亮曾勉东(广州医学院第三附属医院骨科510150)【中图分类号】R683【文献标识码】A【文章编号】1672-5085(2011)46-0112-03【摘要】目的对比分析腰椎峡部内、外部分骨质的抗疲劳特性。方法12例成人新鲜腰L5椎标木模型,随机分为两组,每组6例,分别用咬骨钳咬除腰椎峡部外1/2或内1/2骨质,制作腰椎峡部外1/2缺损和内1/2缺损病理模型。采用游标卡尺对剩余腰椎峡部的宽度进行测量。对腰椎峡部外1/2缺损模型与腰椎峡部内1/2缺损模型的峡部缺损后宽度进行统
2、计对比。将标木固定于脊柱三维运动试验机上,依次将腰椎峡部外1/2缺损和内1/2缺损病理模型标木置于生物材料力学试验机上,分别给予压缩负荷。记录断裂次数进行统计学分析。结果正常L5左侧腰椎峡部宽度为15.06±0.83,正常右侧腰椎峡部宽度为14.85±0.72,左右侧对比P=0.52。腰椎峡部外1/2缺损模型峡部宽度为5.24±0.41,腰椎峡部内1/2缺损模型峡部宽度为5.15±0.34,对比P=0.57o腰椎峡部外1/2缺损模型峡部断裂次数为25160±1
3、019,腰椎峡部内1/2缺损模型峡部断裂次数为18782±3126,对比P=0.006。结论腰椎峡部外1/2缺损模型抗疲劳性优于腰椎峡部内1/2缺损模型,腰椎峡部内1/2承担了更多的腰椎负荷应力。同一应力下,腰椎峡部外1/2更容易疲劳骨折。【关键词】腰椎峡部生物力学AStudyonFatiguecharacteristicsoflumbarspondylolysisandstressdistributionofconductionZhangZhi,WangLe,LvYuming,ZhangLiang,Zengmin
4、gdong,(thethirdAffiliatedHospitalofGuangzhouMedicalCollege,GuangZhou510150)【Abstract】Objective:Tomakepathologicdefectmodelsofisthmusexternal1/2andinternal1/2,Tocompareandanalyzetheanti-fatiguefeaturesofthesetwomodels.Methods:Take12freshlumbarvertebraspecimens.Dividet
5、hese12specimensrandomlyinto2groups.Userongeurtoremoverespectivelytheexternal1/2isthmusandtheinternal1/2isthmusboneandthenmakepathologicaldefectmodels.Useelectricverniercalipertomeasurethewidthoftheremainingisthmus.Comparethewidthoftheexternal1/2isthmusdefectmodelandt
6、heinternal1/2isthmusdefectmodel.Fixthespecimenonspine3Dmovementtestmachine,puttheexternal1/2isthmusdefectmodelandtheinternal1/2isthmusdefectmodelonmechanictestmachine.Recordthebreakagetimesandanalyzethem.Result:ThewidthofthenormalL5leftisthmusportionoflumbarvertebrai
7、s15.06±0.83,therightwidthis14.85±0.72.ThedifferencebetweentheleftwidthandtherightwidthisP=0.52.Theisthmuswidthoftheexternal1/2isthmusdefectmodelis5.24±0.41,theisthmuswidthoftheinternal1/2isthmusdefectmodelis5.15±0.34.Thedifferencebetweenth
8、eexternalandtheinternalisthmuswidthisP=0.57.Thebreakagetimesoftheexternal1/2isthmusdefectmodelare25160±1019,whiletheinternal