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1、EffectsofErzhitianguiDecoctiononVEGFduringembryoimplantationoflutealphasedefectwomenSpeciality:GynecologyofTCMAuthor:LiuXinyuanTutor:Pof.LianFangAbstractObjective:toobservetheeffectofBushenherbsErzhitiangui(EZHTG)decoctionontheformationofendometriumbloodves
2、selsandexploreitsactingmechanism.Methods:64patientsoflutealphasedefectwomenwererandomlydividedintothetestgroup(EZHTGdecoctioncombinedwithwesternmedicine,32cases)andthecontrolgroup(Liuweidihuangdecoctioncombinedwithwesternmedicine,32cases),whichgivenEZHTGdeco
3、ctionandLiuweidihuangdecoctiontopretreatmentthreecycletime.Afterpretreatment,clomipenecombinedHMGweregivento2groups,toobservetheimprovementofsyndromeofTCMbeforeandaftertreatment,serumestradiolandprogestonelevel,bloodflowparametersoftheendometrialandthebloodf
4、lowparametersofUterineartery(PI、RI)onthedayoflutealmetaphasebeforeandaftertreatment,theexpressionofVEGFandcomparedpregnancyrateaftertreatment.Results:1.thetestgroupwasobviouslybetterthanthecontrolgroupinthesyndromepointsofKidney-deficiencybeforeandafterthetr
5、eatment(P＜0．05),2Afterthetreatment,theserumestradiollevelonthedayoflutealmetaphaseofthetestgroupwerehigherthanthecontrolgroup,butthereisnosignificantdifference(P>0．05),theserumprogestonelevelonthedayoflutealmetaphasethetestgroupwasobviouslyhighert
6、hanthecontrolgroup(P<0．05);theserumestradiolandprogestonelevelonthedayoflutealmetaphasein2groups,thetestgroupisobviouslysuperiortothecontrolgroupcomparedwithbeforetreatment．(P<0．05)3.Afterthetreatment,bloodflowparametersRIandRIofendometrialonthedayoflutealme
7、taphaseofthetestgroupislowerthanthecontrolgroup（P＜0．05),;thetestgroupisobviouslysuperiortothecontrolgroupcomparedwithbeforetreatment（P＜0．01),．4.Afterthetreatment,thebloodflowparametersofUterinearteryonthedayoflutealmetaphaseofthetestgroupislowerthanthecontro
8、lgroup（P＜0．05）;thetestgroupisobviouslysuperiortothecontrolgroupcomparedwithbeforetreatment（P＜0．05）5.Afterthetreatment,theexpressionofVEGFinendometriumonthedayoflutealmetaphasewasobviouslyhighert
