二至天癸颗粒对ivfet患者卵巢颗粒细胞fshrmrna表达的影响论文

二至天癸颗粒对ivfet患者卵巢颗粒细胞fshrmrna表达的影响论文

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时间:2018-09-04

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1、ResearchofEr'zhiTianguiGranuletoEffectFSHRmRNAonOvarianGranulosaCellsinVitroFertilization-embryoTransferSpeciality:GynecologyofTCM,theStudyofFemaleSterilityAuthor:YangyangZhengTutor:Prof.FangLianAbstractObjective:ToexplorethemechanismofEr'zhiTianguiGranule(ETG)inimprovingthequa

2、lityofoocyte,theovarianresponseandPregnancyOutcomebymeasuringtherelationshipofFSHRmRNAonovariangranulosacellsinvitrofertilization-embryotransfer.Methods:Inclinicalstudy,65infertilitypatientsofkidneyyindeffciencyundergoingIVF-ETcycleswererandomlydividedinto2groups:thetreatmentgro

3、up(32cases)wastreatedwithETGandGn,thecontrolgroup(33cases)wastreatedwithplaceboandGn.therelationshipofFSHRmRNAonovariangranulosacells,thesyndromescoresofTCM,administrationtimeandnumberofGn,thicknessandtypeofendometrium,thenumberoffertilization,thefertilizationrate,highqualityemb

4、ryorateandpregnancyratewereevaluated.StatisticalanalysiswasdonebySPSS17.0forwindows.Results:(1)Beforetreatmenttwogroupswerecomparableandtherewasnosignificantdifference.(P>0.05).(2)Clinicalsymptomsimprovedmuchintreatmentgroupthancontrolgroup(p<0.05)andthereweresignificantdifferen

5、ces.(3)Beforetreatment,therewerenosignificantdifferencesformbasedendocrineFSH,E2,LH,T,PRLresultsbetweengroupsofpatients(P>0.05),itwascomparable.(4)WhenusingtheGn,therewerenosignificantdifferenceofbasedendocrineFSH,E2,LH,results(P>0.05),itwascomparable.(5)TwogroupsofpatientsHCGda

6、yfollicularmembranebloodflowbyt-testPI,RIcomparisonhadextremelysignificantdifference(P<0.01).(6)Thetreatmentgroupwasobviouslybetterthanthecontrolgroupinimprovingtheamountofoocytes,ratesofmatureoocytes,fertilization,cleavage,high-qualityembryosandpregnancy.Thecomparisonhadextreme

7、lysignificantdifference(P<0.05).(7)ThetreatmentgroupwasobviouslybetterthanthecontrolgroupinimprovingtheLIFlevelinFF,Thecomparisonhadextremelysignificantdifference(P<0.05).Conclusion:Electro-acupuncturehasgoodeffectonimprovingthequalityofoocytes,anditsmechanismmayberelatedtothero

8、leinthehypothalamus-pituitaryovarianaxis.Toprom

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