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ID:46863642
大小:1.31 MB
页数:20页
时间:2019-11-28
《英汉对照分子生物学导论 Chapter 0 Introduction》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、YongWangDepartmentofBiotechnolgySchoolofFoodandBiologicalEngineeringJiangsuUniversityZhenjiang212013P.R.ChinaE-mail:ywang@ujs.edu.cnAbilingualcourseforundergraduatesMolecularBiologySylvainW.LapanDepartmentofBiologyMassachusettsInstituteofTechnologyCambridgeMassa
2、chusetts02139U.S.A.E-mail:slapan@MIT.eduPreparedby&TextbookAnIntroductionofMolecularBiologywithChineseTranslation《英汉对照分子生物学导论》SylvainW.Lapan王勇TeachingActivityTimeTeachingactivityFirstpartUseEnglishtoteach(60minutes)用英语教学SecondpartUseChinesetoexplainthe(30minutes
3、)majorpoints用汉语对主要内容进行讲解JamesD.Watsonetc.MolecularBiologyoftheGeneReferencebooksBenjaminLewinGeneVIIIIntroduction/引言1.Whatismolecularbiology?什么是分子生物学?2.Whatshouldwelearn?我们应该学习什么内容?3.Howtolearn?如何学习?1.Whatismolecularbiology?Molecularbiology:“Howdoesasetofmolecul
4、esmakeadynamiclivingorganism?”Themostfundamentalfeatureofallknownlifeistheabilitytoreproduceandtheabilitytogrow.Iforganismswerenotabletoreproduce,lifewouldbeimpossible.Ifthecelldoesnotgrow,…400kg200kg100kg50kg25kg12.5kgG0G1G2G3G4G5G66.3kg3.1kgG7Atiger?You’rekidd
5、ingme!ThecellgrowsbeforeitdividesDivideGrowDivideProteinsarethekeyplayerReproductionandgrowtharelargelytheworkofproteins.DivideGrowDivideProteinsProteinsProteinsNucleicacids:theinformationcarrierInformationformakingproteinsisstoredinnucleicacids.ProteinsNucleica
6、cids(mainlyDNA)ThecentraldogmaTranscriptionProteinsNucleicacids(mainlyDNA)RNATranslationMolecularbiologystudies…Molecularmechanismsofeverystepinthecentraldogma.中心法则每一步的分子机理2.Whatshouldwelearn?MolecularmechanismsofDNAreplication,transcriptionandtranslation.DNA复制、
7、转录和转译的分子机理。Molecularmechanismsoftranscriptionalandtranslationalregulation.转录与转译调控的分子机理。MolecularmechanismsofDNArecombinationandmutationrepairetc.DNA重组与突变修复等的分子机理。3.Howtolearn?Becausewehavesomanythingstolearn,itisveryeasytogetlostinthesedetails,andsobeforewebegin
8、tostudy,weneedsomeguidingprinciplestogiveasenseofordertomanyofthesedetails.因为我们有这么多内容要学,而一旦深入到细节中又很容易迷失方向,因此在开始学习之前,我们需要一些指导原则来帮助梳理这些细节内容。Theguidingprinciples/指导原则1)E
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