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1、肝癌肝动脉超选择栓塞化疗的临床应用TheClinicalApplicationofSsuperselectiveEmbolismChemotherapyTranshepaticArteryforHepaticCarcimoma何泽清刘国庆汪明全刘兴华罗江平HeZeqing,LiuGuoqing,WangMingquan,LiuXinghua,Luojiangping重庆三峡中心医院CT、MR科(中国404000)DepartmentofCT/MRI,ChongqingThreeGorgesCentralHospital(China404000)中图分类号:
2、R735.7文献标识码:A文章编号:1818・0086(2011)05摘要:目的探讨经肝动脉超选择栓塞化疗在肝癌治疗中的临床应用价值。方法回顾性分析介入法冶疗的639例肝癌患者,对其中312例采用超选择肝动脉栓塞化疗的病例分析造影征像,碘油沉积情况及冶疗效果。结果312例肝癌患者肝动脉造影显示,289例肝癌血管丰富,肿癌染色明显,边缘可见,其中巨块型158例,结节型笛2例,弥漫型42例。术后一月CT复查,X7例碘油致密填塞(其中32例肿块缩小,85例肿块无变化),195例未致密填塞(52例肿块增大,143例肿块大小无变化)o临床随访1年、2年、3年以上生成
3、率分别为84.93%(265/312),69.22%(216/312),53.84%(168/312>结论肝癌肝动脉超选择栓塞化疗,临床疗效显著,应作为一项重要的非手术治疗手段。关键词:肝癌;超选择栓塞化疗;治疗Abstact:ObjectiveToinvestigatetheclinicalvalueoftrans-arterialchemoembolization(TACE)forhepaticcarcinoma.MethodsRetrospectivelyanalyzedthedataof639patientswithhepaticcarcinoma
4、receivedinterventionaltherapy,angiographicsigns,lipiodol-depositedfeaturesandtreatmenteffectivenessin312casesreceivedTACEwereanalyzed.ResultsAmong312casesreceivedhepaticarteriography,289caseshadabundantbloodvessels,stainedobviously,hadvisibleborder.In289cases,thelesionswereclassif
5、iedintothreetypes,giantmasstype(158),nodulartype(112),anddiffusetype(42).CTwereperformedonemonthlaterpost-TACE,lipiodolfulfilledcompletelyin117cases(amongthem,themassdecreasedin32cases,85casedhadnochange),lipiodoldepositedpartlyin195cases(amongthem,themassenlargedin52cases,143case
6、dhadnoobviouslychangeinsize),respective!y・Clinicalfollow-up1year,2years,andmorethan3yearsafterTACE,thesurvivalratewere84.93%(265/312),69.22%(216/312),53.84%(168/312),respective!y.ConclusionTACEforhepaticcarcinomahadevidenttreatmenteffectiveness,andshouldbecomeoneimportantnon-surgi
7、caloperationtherapeuticmeans.Keywords:Hepaticcarcinoma;Superselectiveembolismchemotherapy;treatment原发性肝癌是常见病多发病,严重危害人类生命健康的常见恶性肿瘤之一。近年来中晚期肝癌的肝动脉化疗栓塞已成为肝癌非手术治疗的首选方法,笔者对医院2007年3月-2010年9月采用介入肝动脉栓塞化疗的639例肝癌患者中,回顾性分析,其中312例作超选择肝动脉栓塞化疗的患者报道如下。1材料与方法1.1临床资料本组312例,男207例,女105例,年龄21-78岁,平均5
8、3岁,主要临床症状:右上腹部不适疼痛而就诊,全部病例均有超声、CT