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1、曲安奈德在儿童眼内异物伤玻璃体视网膜手术中的应用广东省粤北人民医院眼科韶关512026;汕头大学医学院附属粤北医院眼科韶关512026目的探讨曲安奈德在儿童眼内异物伤玻璃体视M膜手术中的应用效果,为临床治疗提供指导。方法回顾性分析2011年1月至2016年1月在我院行玻璃体视网膜手术的82例(85眼)儿童眼内异物伤患者的临床资料,并根据手术方式不同分为两组:A组40例(42眼)行眼内异物取岀联合玻切、曲安奈德注射、眼内光凝、硅油填充术;B组42例(43眼)行眼内异物取出联合玻切、眼内光凝、硅油填充术。眼内异物取出术后均随访≥6月。结果82例(85眼)患儿眼内异物均一次手术摘除,出院时视
2、网膜均复位。术后平均随访24.5±12.2月:(1)除2例(2眼)视力检查不合作外,术后视力提高58眼,其中A组33眼(占78.57%,33/42),B组25眼(占58.14%,25/43),两组比较差异有统计学意义(χ2=4.092,P<0.05);43眼术后矫正视力〉0.05(脱盲),其中A组26眼(占61.90%,26/42),B组17眼(占39.53%,17/43),两组比较差异有统计学意义(χ2=4.253,P<0.05)。(2)14例(14眼,16.47%)患儿术后继发视网膜脱离,其中A组3例3眼,发生率为7.14%(3/42),B组11
3、例11眼,发生率为25.58%(11/43),两组比较差异有统计学意义(χ2=5.251,P<0.05)o结论儿童眼内异物伤玻璃体视网膜手术应用曲安奈德可明显提高患者的视力,并可有效预防术后继发性视网膜脱离等并发症的发生,提高了手术的安全性和成功率,值得临床推广。【关键词】曲安奈德;儿童;眼内异物伤;玻璃体视网膜手术Applicationoftriamcinoloneacetonideinvitreo-retinalsurgeryforintraocularforeignbodyinjuryinchildhoodTan丫ehui,ZengGuangchuan,NiaoWu,Li
4、uFangmei,YeYangjun,HuangYaling(DepartmentofOphthalmology,YueBeiPeople'sHospitalinGuangdongprovine,Shaoguan,512026,ChinaDepartmentofOphthalmology,theAffiliatedYueBeiPeople'sHospital,MedicalCollegeofShantouUniversity,Shaoguan,512026,China)[Abstract]PurposeTodiscusstheclinicalapplicationefficacyoftria
5、mcinoloneacetonide(TA)invitreo-retinalsurgeryforintraocularforeignbodyinjuryinchildhood,inordertoguideclinicaltreatment.MethodsWestudiedtherelatedclinicaldataof82cases(85eyes)intraocularforeignbodyinjuryinchildwhoreceivedvitreo-retinalsurgeryinourhospitalfromJan,2011toJan,2016,anddividedthemintotwo
6、differentgroupsaccordingtothestylesofvitreo-retinalsurgery.40cases(42eyes)ofgroupAweretreatedbyintraocularforeignbodiesextractioncombinedwithvitrectomy,injectingTAintothevitreouscavity,intraocularphotocoagulationandfillingwithsiliconeoil.42cases(43eyes)ofgroupBweretreatedbyintraocularforeignbodiese
7、xtractioncombinedwithvitrectomy,intraocularphotocoagulationandfillingwithsiliconeoil.Allthepatientswerefollowed-upmorethan6monthsafterthesurgeryofintraocularforeignbodiesextraction.ResultsAllintraocularfore