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时间:2020-05-24
《部分脾动脉栓塞术治疗肝硬化门静脉高压症的疗效及安全性观察.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、第26卷第1期第33页临床消化病杂志Vol26No1P332O14年2月ChinJClinGastroenterolFeb2Ol4doi:10.3870/lcxh.j.issn.1005—541X.2014.01.11部分脾动脉栓塞术治疗肝硬化门静脉高压症的疗效及安全性观察占国清,谭华炳,李芳,李儒贵,李刚,张薇薇(湖北医药学院附属人民医院肝病研究所,湖北十堰442000)摘要:[目的]探讨部分脾动脉栓塞术(PSE)治疗肝硬化门静脉高压症的临床疗效及安全性。[方法]对48例不同原因肝硬化门静脉高压患者
2、行PSE治疗,观察术前及术后1周、1、3、6个月血常规、肝功能、脾脏厚度、脾静脉和门静脉内径、Child—Pugh分级变化及并发症情况。[结果-IPSE后患者白细胞和血小板计数均明显升高(P<0.01);术后1个月患者脾静脉和门静脉内径明显缩小(Po.05);PSE后并发症
3、较多,但未发现严重的并发症。[结论]PSE治疗肝炎肝硬化门静脉高压症合并脾功能亢进安全有效。关键词:肝硬化;部分脾动脉栓塞术;脾功能亢进;高血压,门静脉中图分类号:R575.2文献标志码:A文章编号:1005—541X(2014)01033—04ClinicalobservationoneffectandsecurityofpartialsplenicarteryembolizationinpatientswithlivercirrhosisandportalhypertensionZHANGuo—q
4、ing,TANHua—bing,LJFang,LIRu—gui,LIGang,ZHANGWei—wei(InstituteofHepatology,RenminHospital,HubeiUniversityofMedicine,Shiyan442000,China)Abstract:EObjective]Toinvestigatethetherapeuticeffectandsecurityofpartialsplenicarteryemboli—zation(PSE)inpatientswithI
5、ivercirrhosisandportalhypertension.[-Methods]Forty-eightcaseswithliv—ercirrhosisandportalhypertensionweretreatedwithPSE。Thebloodroutinetest,liverfunction,thethick—nessofthespleen,splenicvein(SV)andportalvein(PV)diameter,Child—Pughclassificationchangesan
6、dthecomplicationswereobservedrespectivelybeforePSEandlweek,1month,3months,6monthsafterPSE.[Results]Aftertheoperation,thenumbersofleucocytesandplateletsweresignificantlyincreased(P7、1),andspleenthicknessbecamemuchsmallerafter6months(P<0.05),Prothrombintime(PT)wassignificantlyshortenedandTBilincreased(P<0.01),buttherewasnosignificantdifferenceinAST,ALTandChild_Pughgradebeforeandafteroperation(P>0.05).ManycomplicationshappenedafterPS8、E,butnoseriouscomplicationswerefound.[Conclusion]PSEissafeandeffectiveforcuringcirrhosistogetherwithhyper—splenismandportalhypertension.Keywords:livercirrhosis;partialsplenicembolization;hypersplenism;hypertension,portal肝硬化门静脉高压症
7、1),andspleenthicknessbecamemuchsmallerafter6months(P<0.05),Prothrombintime(PT)wassignificantlyshortenedandTBilincreased(P<0.01),buttherewasnosignificantdifferenceinAST,ALTandChild_Pughgradebeforeandafteroperation(P>0.05).ManycomplicationshappenedafterPS
8、E,butnoseriouscomplicationswerefound.[Conclusion]PSEissafeandeffectiveforcuringcirrhosistogetherwithhyper—splenismandportalhypertension.Keywords:livercirrhosis;partialsplenicembolization;hypersplenism;hypertension,portal肝硬化门静脉高压症
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