欢迎来到天天文库
浏览记录
ID:55656920
大小:628.72 KB
页数:5页
时间:2020-05-23
《经导管化疗栓塞联合经皮微波消融治疗中晚期肝癌64例的预后分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、介入放射学杂志2014年6月第23卷第6期JInterventRadiol2014,Vo1.23,No.6.——477.——·肿瘤介入Tumorintervention·经导管化疗栓塞联合经皮微波消融治疗中晚期肝癌64例的预后分析万豪光,许伟,徐浩,顾玉明,祖茂衡,王勇,宗迎迎【摘要】目的探讨经导管肝动脉化疗栓塞(TACE)联合经皮微波消融术(MWA)治疗中晚期肝癌预后的影响因素。方法2011年1月一20l2年7月,64例中晚期肝癌患者行TACE联合MWA治疗,收集14项可能影响预后的因素作回顾性单因素与多因素分析。单因素分
2、析采用Kaplan—Meier模型及Log—rank检验.多因素分析采用Cox比例风险模型。结果64例中晚期肝癌患者治疗后l、1.5、2年总生存率分别为75.8%、48.4%、33.9%。单因素分析及Cox回归分析结果显示肿瘤大小、肿瘤数目、门静脉癌栓、血清AFP值、肿瘤期别、服用索拉菲尼等6项因素与预后有关。结论肿瘤大小、肿瘤数目、门静脉癌栓、血清AFP值、肿瘤期别是影响介人综合治疗预后的危险因素,服用索拉菲尼是影响预后的保护性因素。【关键词】癌,肝细胞;化疗栓塞;微波消融;预后中图分类号:R735.7文献标志码:A文章编
3、号:1008—794X(2014)一06—0477—05TranscatheterarterjalchemoembolizationcombinedwititpercutaneousmicrowaveaMationforthetreatmentofintermediate—advancedhepatocellularcarcinoma:analysisofprognosticfactorsin64casesWANHao-guang,XUWei,XUHao,GUYu—ming,ZUMoo—heng,WANGYong,ZONGY
4、ing—ying.DepartmentoflnterventionalRadiology,AfiliatedHospitalofXuzhouMedicalCollege,Xuzhou,JiangsuProvince221002,ChinaCorrespondingauthor:XUWei,E—mail:xuweiO202@gmm1.com【Abstract】ObjectiveToinvestigatetheprognosticfactorsaffectingtheoutcomeofpatientswithintermedia
5、te—advancedhepatocellularcarcinoma(HCC)receivingtranseatheterarterialchemoembolization(TACE)combinedwithpercutaneousmicrowaveablation(MWA).MethodsDuringtheperiodfromJanuary2011toJuly2012atauthors’hospita1.atota1of64patientswithintermediate-advancedHCCweretreatedwit
6、hTACEtogetherwithMWA.Fourteenpotentialvariableswhichmightaffecttheprognosiswerecolletedandwereretrospectivelyanalyzed.Kaplan-Meiermodelandlog—ranktestwereusedforsinglefactoranalysis,whileCoxregressionmodelwasusedformultiplefactoranalysis.ResultsTheone—year,1.5-year
7、and2-yearoverallsurvivalrateswere75.8%,48.4%and33.9%,respectively.SinglefactoranalysisandCoxregressionanalysisindicatedthatsixfactors,i.e.tumorsize,numberoftumors,portalveintumorthrombus,serlmoL—fetoproteinlevel,tumorstagingandoraladministrationofsorafenib,borearel
8、ationshiptotheprognosis.ConclusionThetumorsize,numberoftumors,portalveintumorthrombus,serumoL—fetoproteinlevelandtumorstagingareriskfactorsinflue
此文档下载收益归作者所有