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时间:2020-05-15
《甲氨蝶呤配伍米非司酮治疗剖宫产术后子宫瘢痕妊娠的效果观察.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·药物与临床·中国当代医药2014年12月第21卷第35期甲氨蝶呤配伍米非司酮治疗剖宫产术后子宫瘢痕妊娠的效果观察刘晶辽宁省东港市中医院,辽宁东港118300【摘要】目的探讨甲氨蝶呤配伍米非司酮治疗剖宫产术后子宫瘢痕妊娠的临床效果。方法选取2008年8月~2014年8月本院收治的剖宫产术后子宫瘢痕妊娠患者80例,将其随机分为观察组和对照组,各40例,对照组采用甲氨蝶呤治疗,观察组在对照组的基础上配伍米非司酮治疗,两组均治疗6d,比较两组的临床疗效,记录血B—HCG降至正常时问、包块大小及住院时间。结果观察组总有
2、效率为87.5%,高于对照组的70.0%,差异有统计学意义(P<0.05)。观察组血B—HCG降至正常时间及住院时间短于对照组,包块大小小于对照组,差异有统计学意义(P3、inedwithmifepristoneinthetreatmentofcesareanscarpregnancyLIUringChineseMedicineHospitalofDonggangCityinLiaoningProvince,Donggang118300,China【Abstract】0bjectiveToinvestigatetheclinicaleffectsofmethotrexatecombinedwithmifepristoneinthetreatmentofcesareanscarpr4、egnancy.Methods80patientswithcesareanscarpregnancyadmittedtoourhospitalfromAugust2008toAugust2014wereselectedandrandomlydividedintoobservationgroupandcontrolgroup,40casesineachgroup,methotrexatewastakentothecontrolgroup,mifepristonewasaddedtotheobservationgr5、oupbasedoncontrolgrouptreatment,bothgroupsweretreatedforsixdays.Theclinicalefficacyofthetwogroupswascompared,serum3-HCGde-creasedtonormaltime,masssizeandlengthofstayintwogroupswererecorded.ResultsThetotaleffectiverateofob—servationgroupwas87.5%,higherthantha6、tofcontrolgroup(70.0%),withstatisticaldifference(P<0.05).Theserump—HCGdecreasedtonormaltimeandlengthofstayinobservationgroupwasshorterthanthatincontrolgrouprespective—ly,themasssizeinobservationgroupwaslessthanthatincontrolgroup,withstatisticaldifference(P<07、.05).ConclusionMethotrexatecombinedwithmifepristoneinthetreatmentofcesareanscarpregnancyhassignificanteffect,canacceler—ateblood13-HCGtonormaltime,shoflenhospitalizationtime.【Keywords】Methotrexate;Mifepristone;Cesareansection;Scarpregnancy剖官产术后子宫瘢痕妊娠是指受精卵着床于8、既11.27)岁;孕2~7次,平均(4.20±1.38)次;产1~2次,往有剖宫产史孕妇子宫下段剖宫产术后子宫瘢痕处Ⅲ,剖宫产1~2次;剖宫产术后至瘢痕妊娠发病时间最短是一种特殊的异位妊娠,为剖宫产的远期并发症之5个月,最长15年,平均(3.19+1.06)年;均有停经史,一停经时间39—80d,平均(45.82_+12.38)d。纳入标准:。瘢痕妊娠有极高的危害性,如早孕漏诊误诊而盲
3、inedwithmifepristoneinthetreatmentofcesareanscarpregnancyLIUringChineseMedicineHospitalofDonggangCityinLiaoningProvince,Donggang118300,China【Abstract】0bjectiveToinvestigatetheclinicaleffectsofmethotrexatecombinedwithmifepristoneinthetreatmentofcesareanscarpr
4、egnancy.Methods80patientswithcesareanscarpregnancyadmittedtoourhospitalfromAugust2008toAugust2014wereselectedandrandomlydividedintoobservationgroupandcontrolgroup,40casesineachgroup,methotrexatewastakentothecontrolgroup,mifepristonewasaddedtotheobservationgr
5、oupbasedoncontrolgrouptreatment,bothgroupsweretreatedforsixdays.Theclinicalefficacyofthetwogroupswascompared,serum3-HCGde-creasedtonormaltime,masssizeandlengthofstayintwogroupswererecorded.ResultsThetotaleffectiverateofob—servationgroupwas87.5%,higherthantha
6、tofcontrolgroup(70.0%),withstatisticaldifference(P<0.05).Theserump—HCGdecreasedtonormaltimeandlengthofstayinobservationgroupwasshorterthanthatincontrolgrouprespective—ly,themasssizeinobservationgroupwaslessthanthatincontrolgroup,withstatisticaldifference(P<0
7、.05).ConclusionMethotrexatecombinedwithmifepristoneinthetreatmentofcesareanscarpregnancyhassignificanteffect,canacceler—ateblood13-HCGtonormaltime,shoflenhospitalizationtime.【Keywords】Methotrexate;Mifepristone;Cesareansection;Scarpregnancy剖官产术后子宫瘢痕妊娠是指受精卵着床于
8、既11.27)岁;孕2~7次,平均(4.20±1.38)次;产1~2次,往有剖宫产史孕妇子宫下段剖宫产术后子宫瘢痕处Ⅲ,剖宫产1~2次;剖宫产术后至瘢痕妊娠发病时间最短是一种特殊的异位妊娠,为剖宫产的远期并发症之5个月,最长15年,平均(3.19+1.06)年;均有停经史,一停经时间39—80d,平均(45.82_+12.38)d。纳入标准:。瘢痕妊娠有极高的危害性,如早孕漏诊误诊而盲
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