欢迎来到天天文库
浏览记录
ID:55057841
大小:207.99 KB
页数:3页
时间:2020-05-08
《乙型肝炎病毒感染患者的联合检测临床意义-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·389O·中华医院感染学杂志2014年第24卷第15期ChinJNosocomiolVo1.24No.152014doi:10.11816/cn.ni.2014—135027乙型肝炎病毒感染患者的联合检测临床胡旭,刘红霞,任东方(南阳市中心医院检验科,河南南阳473001)摘要:目的探讨乙型肝炎病毒(HBV)感染患者血清乙型肝炎五项标志物、乙型肝炎DNA(HBV-DNA)定量与乙型肝炎前S1抗原(PreSIAg)联合检测的临床意义,以期能为临床诊断提供参考。方法2012年1月一2013年7月对诊治的120例
2、HBV感染患者空腹抽取静脉血检测乙型肝炎五项标志物、HBV-DNA定量与PreSIAg,分析其结果,采用SPSS17.0软件进行统计分析。结果乙型肝炎五项标志物检测结果HBsAg+HBsAb、HBsAg+HBeAg+HBcAb、HBsAg+HBeAb+HBcAb、HBsAg+HBeAg、HBsAg+HBeAb、HBsAg+HBcAb模式分别占2.50、25.84、45.OO、1O.OO、5.83%、1O.83,PreSIAg阳性率为60.83,HBV-DNA阳性率为67.5O%;HBV—DNA阳性患者中Pre
3、SlAg阳性率74.O4%高于HBeAg阳性率45.68,差异有统计学意义(P4、.HUXu,LIUHong—xia,RENDong—fang(NanyangCentralHospitalofHenanProvince,Nanyang,Henan473001,China)Abstract:OBJECTIVEToinvestigatetheclinicalsignificanceofjointdetectionoffivehepatitisBmarkers,hepati—tisBDNA(HBV-DNA)quantificationandhepatitisBPreS1antigen(PreS15、Ag)inserumofpatientswithhepati—tisBvirus(HBV)infectionSOastoprovidereferencesforclinicaldiagnosis.METHODSForthe120patientswithHBVinfectiontreatedduringJan.2012一Ju1.2013,peripheralvenousbloodsamplesweretakenonanemptystomachfortestingoffivehepatitisBmarkers,H6、BV-DNAquantificationandPreSIAg.TheresultswereanalyzedbyusingSPSS17.0sotwer.RESULTSThetestingresultsforthefivehepatitisBmarkersindicatedthatHBsAg+论HBsAb意,HBSAg+HBeAg+HBcAb,HBsAg+HBeAb+HBcAb,HBsAg+HBeAg,HBsAg+HBeAbandHB—sAg+HBcAbaccountedfor2.50,25.84,45.OO,17、O.OO,5.83and10.00%,respectively.Theposi—tiverateofpreS1Agwas60.83,andthepositiverateHBV—DNAwas67.50.InpatientswithpositiveHBV-著DNA,thepositiverateofPreSIAgwas74.04,higherthan45.68oftheHBeAg,thedifferencewasstatisti—eallysignificant(P<0.05).CONCLUSIONThejoin8、tdetectionofthefivehepatitisBmarkers,HBV-DNA,andPreSIAgcandiagnosethereplicationandinfectivityofHBVmoreaccurately.Keywords:HepatitisBvirus;FivehepatitisBmarkers;HBVDNAquantification;PreS1AntigenofHBV乙型
4、.HUXu,LIUHong—xia,RENDong—fang(NanyangCentralHospitalofHenanProvince,Nanyang,Henan473001,China)Abstract:OBJECTIVEToinvestigatetheclinicalsignificanceofjointdetectionoffivehepatitisBmarkers,hepati—tisBDNA(HBV-DNA)quantificationandhepatitisBPreS1antigen(PreS1
5、Ag)inserumofpatientswithhepati—tisBvirus(HBV)infectionSOastoprovidereferencesforclinicaldiagnosis.METHODSForthe120patientswithHBVinfectiontreatedduringJan.2012一Ju1.2013,peripheralvenousbloodsamplesweretakenonanemptystomachfortestingoffivehepatitisBmarkers,H
6、BV-DNAquantificationandPreSIAg.TheresultswereanalyzedbyusingSPSS17.0sotwer.RESULTSThetestingresultsforthefivehepatitisBmarkersindicatedthatHBsAg+论HBsAb意,HBSAg+HBeAg+HBcAb,HBsAg+HBeAb+HBcAb,HBsAg+HBeAg,HBsAg+HBeAbandHB—sAg+HBcAbaccountedfor2.50,25.84,45.OO,1
7、O.OO,5.83and10.00%,respectively.Theposi—tiverateofpreS1Agwas60.83,andthepositiverateHBV—DNAwas67.50.InpatientswithpositiveHBV-著DNA,thepositiverateofPreSIAgwas74.04,higherthan45.68oftheHBeAg,thedifferencewasstatisti—eallysignificant(P<0.05).CONCLUSIONThejoin
8、tdetectionofthefivehepatitisBmarkers,HBV-DNA,andPreSIAgcandiagnosethereplicationandinfectivityofHBVmoreaccurately.Keywords:HepatitisBvirus;FivehepatitisBmarkers;HBVDNAquantification;PreS1AntigenofHBV乙型
此文档下载收益归作者所有