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时间:2020-05-07
《AFU、PT、Cp、T4联合检测在乙型肝炎患者中的临床意义-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、临京医学工程2014年9月第21卷第9期·1173··论著·(临床研究)AFU、PT、Cp、T4联合检测在乙型肝炎患者中的临床意义蔡高荣,曹宝华2,肖芳信(中山大学附属第一医院检验科,广东广州510080;中山大学附属第三医院检验科,广东广州510630)【摘要】目的探讨乙型肝炎患者血清甲状腺素(T)、铜蓝蛋白(Cp)、OL—L一岩藻糖苷酶(AFU)和凝血酶原时间(PT)水平变化与肝功能损害程度的相关性及其临床意义。方法187病例分成慢性肝炎组、重型肝炎组和肝硬化组,同时选择同期进行体检的健康人作为对照组,分别检测T、Cp、AFU和PT,并
2、进行统计学分析。结果各病例组AFU、PT和T与正常对照组比较,差异均具有统计学意义(P<0.05);肝硬化组AFU明显低于其他两个病例组(P0.05)。结论联合检测T,cp,ALT和PT对病毒性肝炎的早期和鉴别诊断、病情判断以及疗效和预后评估有重要参考价值。【关键词】乙型肝炎;甲状腺素;铜蓝蛋白;一L一岩藻糖苷酶;
3、凝血酶原时间中图分类号:R512.6+2文献标识码:Adoi:10.3969/j.issn.1674—4659.2014.09.1173DetectionofAFU,PT,CpandT4inPatientswithHepatitisBDiseaseandItsClinicalSignificanceCAIGaorong,CAOBaohua。,XIAOFangxinClinicalLaboratory,theFirstAffiliatedHospitalofSunYat-senUniversity,Guangzhou510080,China,
4、"。ClinicalLaboratory,theThirdAffili~edHospitalofSunYat-senUniversity,Guangzhou510630,China)[Abstract】ObjectiveToexplorethechangesoflevelsofthyroxine(T4),ceruloplasmin(Cp),O/一L-fucosidase(AFU),prothrombintime(Frr),thecorrelationwithliverfunctiondamagedegreeanditsclinicalsig
5、nificance.Methods187cases(casesgroup)weredividedintochronichepatitisgroup(n=104),severehepatitisgroup(n=43)andlivercirrhosisgroup(n=40),and168casesofhealthypeoplewereselectedasthecontrolgroup.ThelevelsofT4,Cp,AFUandofallgroupsweredetected.ResultsComparedwiththecontrolgroup
6、,thelevelsofAFU,PTandT4ofchronichepatitisgroup,severehepatitisgroupandlivercirrhosisgroupwerestatisticallydifferent(allP7、PTamongchronichepatitisgroup,severehepatitisgroupandlivercirrhosisgroupwerestatisticallysignificant(P<0.05).ThelevelofT4ofchronichepatitisgroupwassignificantlyhigherthanthatofseverehepatitisgroupandlivercirrhosisgroup(bothP8、icantlylowerthanthatofthecontrolgroup.chronichepatitisgroupandlivercirrhosisgroup(P
7、PTamongchronichepatitisgroup,severehepatitisgroupandlivercirrhosisgroupwerestatisticallysignificant(P<0.05).ThelevelofT4ofchronichepatitisgroupwassignificantlyhigherthanthatofseverehepatitisgroupandlivercirrhosisgroup(bothP8、icantlylowerthanthatofthecontrolgroup.chronichepatitisgroupandlivercirrhosisgroup(P
8、icantlylowerthanthatofthecontrolgroup.chronichepatitisgroupandlivercirrhosisgroup(P
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