欢迎来到天天文库
浏览记录
ID:58299087
大小:204.59 KB
页数:3页
时间:2020-05-08
《乙型肝炎病毒感染患者发生肝硬化的危险因素分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·25OO·中华医院感染学杂志2014年第24卷第10期ChinJNosocomiolVo1.24No.102014doi:10.11816/cn.ni.2014—133610·论著·乙型肝炎病毒感染患者发生肝硬化的危险因素分析苏毅,李传腾,刘玉娟(贵州省遵义医学院第一附属医院感染科,贵州遵义563003)摘要:目的探讨乙型肝炎病毒(HBV)感染患者发生肝硬化的相关危险因素,为临床干预提供参考。方法选取医院2010年1月一2012年12月282例慢性乙型肝炎患者作为研究对象,根据检查结果分为肝硬化组、健康恢复组及非肝硬化组,对比各组患者相关指标及基
2、本情况进行分析;采用SPSS18.0软件进行统计分析,计量资料以矗s表示,组问比较采用Bonferroni校正,多组计量资料平均水平的比较采用方差分析;计数资料采用。检验,采用Spearman相关系数进行变量间相关度检验。结果肝硬化组HBsAg水平I临界指数≥2000患者26例,占42.62;明显高于非硬化组的21.61,两组比较差异有统计学意义(P3、硬化家庭史、饮酒是慢性乙型肝炎肝硬化的危险因素,且肝硬化组的ALT、HBV-DNA、甲胎蛋白、血清铁、转铁蛋白饱和度指标均高于非硬化组,两组比较差异有统计学意义(P4、spatientsSUYi.LIChuan—teng。LIUYu-juan(TheFirstAffiliatedHospitalinGuizhouZunyiMedicalCollege,Zunyi,Guizhou563003,China)Abstract:OBJECTIVEToinvestigatetherelevantriskfactorscausingcirrhosistohepatitisBvirus(HBV)pa—tientssoastoprovideareferenceforclinicalintervention.METHODSAtot5、alof282casesofchronicHBVpatientsfromJan2010toDec2012wereselectedasstudysubjectsandweredividedintocirrhosisgroup,healthrecoverygroupandnon-cirrhosisgroupaccordingtotestresults;therelevantindexesandbasicconditionofpatientsofeachgroupwereanalyzed;SPSS18.0softwarewasadoptedforstat6、isticalanalysis,measurementdatawereexpressedbyx±s,andcomparisonamonggroupswascalibratedbyBonferroni,andvarianceanalysiswasusedforcomparingtheaveragelevelofthemeasurementdataamongmulti—groups;Chi—squaretestwasadoptedforenumerationdataandSpearmancorrelationcoefficientwasadoptedf7、orrelevancytestamongvariables.RESULTSAtotalof54pa—tientsofthecirrhosisgroupwithHBsAgcriticalexponenttobe2000ormore,accountingfor88.52,whichwassignificantlyhigherthanthatofnon-cirrhosisgroup;therewassignificantdifferencebetweenthetwogroups(P<0.05).Theverticalinfectionratesofhea8、lthrecoverygroup,non-cirrhosisgroupandcirrhosisgroupwere5O.85
3、硬化家庭史、饮酒是慢性乙型肝炎肝硬化的危险因素,且肝硬化组的ALT、HBV-DNA、甲胎蛋白、血清铁、转铁蛋白饱和度指标均高于非硬化组,两组比较差异有统计学意义(P4、spatientsSUYi.LIChuan—teng。LIUYu-juan(TheFirstAffiliatedHospitalinGuizhouZunyiMedicalCollege,Zunyi,Guizhou563003,China)Abstract:OBJECTIVEToinvestigatetherelevantriskfactorscausingcirrhosistohepatitisBvirus(HBV)pa—tientssoastoprovideareferenceforclinicalintervention.METHODSAtot5、alof282casesofchronicHBVpatientsfromJan2010toDec2012wereselectedasstudysubjectsandweredividedintocirrhosisgroup,healthrecoverygroupandnon-cirrhosisgroupaccordingtotestresults;therelevantindexesandbasicconditionofpatientsofeachgroupwereanalyzed;SPSS18.0softwarewasadoptedforstat6、isticalanalysis,measurementdatawereexpressedbyx±s,andcomparisonamonggroupswascalibratedbyBonferroni,andvarianceanalysiswasusedforcomparingtheaveragelevelofthemeasurementdataamongmulti—groups;Chi—squaretestwasadoptedforenumerationdataandSpearmancorrelationcoefficientwasadoptedf7、orrelevancytestamongvariables.RESULTSAtotalof54pa—tientsofthecirrhosisgroupwithHBsAgcriticalexponenttobe2000ormore,accountingfor88.52,whichwassignificantlyhigherthanthatofnon-cirrhosisgroup;therewassignificantdifferencebetweenthetwogroups(P<0.05).Theverticalinfectionratesofhea8、lthrecoverygroup,non-cirrhosisgroupandcirrhosisgroupwere5O.85
4、spatientsSUYi.LIChuan—teng。LIUYu-juan(TheFirstAffiliatedHospitalinGuizhouZunyiMedicalCollege,Zunyi,Guizhou563003,China)Abstract:OBJECTIVEToinvestigatetherelevantriskfactorscausingcirrhosistohepatitisBvirus(HBV)pa—tientssoastoprovideareferenceforclinicalintervention.METHODSAtot
5、alof282casesofchronicHBVpatientsfromJan2010toDec2012wereselectedasstudysubjectsandweredividedintocirrhosisgroup,healthrecoverygroupandnon-cirrhosisgroupaccordingtotestresults;therelevantindexesandbasicconditionofpatientsofeachgroupwereanalyzed;SPSS18.0softwarewasadoptedforstat
6、isticalanalysis,measurementdatawereexpressedbyx±s,andcomparisonamonggroupswascalibratedbyBonferroni,andvarianceanalysiswasusedforcomparingtheaveragelevelofthemeasurementdataamongmulti—groups;Chi—squaretestwasadoptedforenumerationdataandSpearmancorrelationcoefficientwasadoptedf
7、orrelevancytestamongvariables.RESULTSAtotalof54pa—tientsofthecirrhosisgroupwithHBsAgcriticalexponenttobe2000ormore,accountingfor88.52,whichwassignificantlyhigherthanthatofnon-cirrhosisgroup;therewassignificantdifferencebetweenthetwogroups(P<0.05).Theverticalinfectionratesofhea
8、lthrecoverygroup,non-cirrhosisgroupandcirrhosisgroupwere5O.85
此文档下载收益归作者所有