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《医务人员乙型肝炎病毒感染相关危险因素分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·2312·中华医院感染学杂志2014年第24卷第9期ChinJNosocomiolVo1.24No.92014doi:10.11816/cn.ni.2014—132096●论著医务人员乙型肝炎病毒感染相关危险因素分析聂利,吴晓英,李远(重庆医科大学附属永川医院院感科,重庆402160)摘要:目的了解医务人员乙型肝炎病毒(HBV)感染现状与相关危险因素,为医务人员HBV防治提供参考依据。方法将882名医务人员按与血液接触密切程度分为血液少接触组、血液一般性接触组、血液密切接触组;用酶联免疫吸附试验(ELISA)检测HBV5项血清学标志物:HBsAg、抗-
2、HBs、HBeAg、抗一HBe和抗一HBc;自行设计调查问卷调查人口学特征、乙型肝炎疫苗接种及参加HBV防护知识培训状况。结果医务人员HBV感染率为23.92,免疫率为5O.11%,易感率为29.49;血液少接触组、一般性接触组、密切接触组HBV感染率分别为24.35、18.82%、33.97,HBV免疫率分别43.26、66.76、30.77,HBV易感率分别为36.27、18.82、43.59,3组比较差异有统计学意义(P3、密切接触程度呈正相关,医务人员HBV感染风险男性高于女性,低学历高于高学历,应重视HBV防治知识培训与预防接种。关键词:医务人员;乙型肝炎病毒;感染;免疫;相关因素中图分类号:R512.62文献标识码:A文章编号:1005—4529(2014)09-2312-03RiskfactorsforhepatitisBvirusinfectioninmedicalstattNIELi,WuXiao—ying,LIYuan(YongchuanAffiliatedHospithlofChongqingMedicalUniversity,Chongqing40216O4、,China)Abstract:OBJECTIVETounderstandtheprevalenceofhepatitisBvirus(HBV)infectioninmedicalstaffandana—lyzetherelatedriskfactorssoastoprovideguidanceforpreventionandtreatmentofHBVinfectioninthemedicalstaff.METHODSTotally882medicalstaffweredividedinto,accordingtothedegreeoftheircon5、tactingtoblood,thelesscontactgroup,thegeneralcontactgroup,andtheclosecontactgroup,thentheenzyme—linkedimmu—nosorbentassaywasperformedtodetectthefiveserologicalmarkersofHBV,includingHBsAg,anti—HBs,HBeAg,anti-HBe,andanti-HBc;thedemographiccharacteristics,statusofvaccinationofhepati6、tisBvaccine,andattendancetotrainingofpreventionknowledgeofHBVwereinvestigatedbyusingself-designedquestionnaire.RESULTSTheincidenceofHBVinfectionwas23.92inthemedicalstaff,theimmunizationratewas50.11,andthesusceptibleratewas29.49.TheincidencerateofHBVinfectionwas24.35inthelessconta7、ctgroup,18.82inthegeneralcontactgroup,33.97intheclosecontactgroup;therateofimmunizationtoHBVwas43.26inthelesscontactgroup,66.76inthegeneralcontactgroup,30.77intheclosecontactgroup;therateofthesusceptibletoHBVinfectionwas36.27inthelesscontactgroup,18.82inthegeneralcontactgroup,43.8、59intheclosecontactgroup,withsignificant
3、密切接触程度呈正相关,医务人员HBV感染风险男性高于女性,低学历高于高学历,应重视HBV防治知识培训与预防接种。关键词:医务人员;乙型肝炎病毒;感染;免疫;相关因素中图分类号:R512.62文献标识码:A文章编号:1005—4529(2014)09-2312-03RiskfactorsforhepatitisBvirusinfectioninmedicalstattNIELi,WuXiao—ying,LIYuan(YongchuanAffiliatedHospithlofChongqingMedicalUniversity,Chongqing40216O
4、,China)Abstract:OBJECTIVETounderstandtheprevalenceofhepatitisBvirus(HBV)infectioninmedicalstaffandana—lyzetherelatedriskfactorssoastoprovideguidanceforpreventionandtreatmentofHBVinfectioninthemedicalstaff.METHODSTotally882medicalstaffweredividedinto,accordingtothedegreeoftheircon
5、tactingtoblood,thelesscontactgroup,thegeneralcontactgroup,andtheclosecontactgroup,thentheenzyme—linkedimmu—nosorbentassaywasperformedtodetectthefiveserologicalmarkersofHBV,includingHBsAg,anti—HBs,HBeAg,anti-HBe,andanti-HBc;thedemographiccharacteristics,statusofvaccinationofhepati
6、tisBvaccine,andattendancetotrainingofpreventionknowledgeofHBVwereinvestigatedbyusingself-designedquestionnaire.RESULTSTheincidenceofHBVinfectionwas23.92inthemedicalstaff,theimmunizationratewas50.11,andthesusceptibleratewas29.49.TheincidencerateofHBVinfectionwas24.35inthelessconta
7、ctgroup,18.82inthegeneralcontactgroup,33.97intheclosecontactgroup;therateofimmunizationtoHBVwas43.26inthelesscontactgroup,66.76inthegeneralcontactgroup,30.77intheclosecontactgroup;therateofthesusceptibletoHBVinfectionwas36.27inthelesscontactgroup,18.82inthegeneralcontactgroup,43.
8、59intheclosecontactgroup,withsignificant
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