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《慢性乙型肝炎病毒感染不同免疫状态主要证候的研究-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·102·中华中医药杂志(原中国医药学报)2014年1月第29卷第1期CJTCMP,January2014,Vo1.29,No.1论著·慢性乙型肝炎病毒感染不同免疫状态主要证候的研究杨丽莎,梁志清,范剑薇,吴淋玲,苏元英,张兵(桂林医学院附属医院中医科,桂林541001)摘要:目的:通过对慢性乙型肝炎病毒(HBV)感染不同免疫状态证候的研究,了解各不同免疫状态的主要证候。方法:采用免疫学分类、证候分型及临床流行病学调查等方法,选择慢性HBV感染免疫耐受、免疫清除和免疫不全3个状态各200例,进行主要证候分析。结果:慢性HBV感染3
2、个不同免疫状态出现的证候均有肝郁脾虚、肝肾阴虚、肝郁气滞、湿热内蕴、脾气虚、气阴不足、心肝郁热、肝血虚、肺脾气虚、血瘀证、脾。肾阳虚等。不同免疫状态中免疫耐受组肝郁脾虚、脾气虚及心肝郁热证高于其他两组(P<0.05);免疫清除组湿热内蕴和肝郁气滞证高于其他两组(P3、),广西科学研究与技术开发计划项目(桂科攻No.10124001B),广西卫生厅医疗卫生计划课题(No.Z2007190)StudyofdifferentimmunestatusofmainTCMsyndromesofchronicHBVinfectionYANGLi·sha,LIANGZhi—qing,FANJian—wei,WULin—ling,SUYuan—ying,ZHANGBing(DepartmentofTCM,AffiliatedHospitalofGuilinMedicalUniversity,Guilin54104、01,China)Abstract:Objective:ThronghtheresearchofdiferentimmunestatesyndromesofchronicHBVinfection,tounderstandthedifferentimmunestatusofTCMsyndromedistribution.Methods:Usingimmunologicalclassification,syndromesandclinicalepidemiologysurveymethod,select200HBVpatientsof5、differentstatesamongimmunetolerance,immuneclearanceandimmunedeficiencyrespectively,andhaveamainsyndromeanalysis.Results:ThreedifferentimmunestatesofchronicHBVinfectionallhavesyndromesofliverdepressionandspleendeficiency,yindeficiencyofliverandkidney,liverqistagnation,6、accumulationofdamp—heat,spleenqideficiency,qiandyindeficiency,heartandliverstagnatedheat,deficiencyofliverblood,lungandspleenqideficiency,bloodstasis,deficiencyofspleenandkidneyyang.Inimmunetolerancegroup,incidencesofliverdepressionspleendeficiency,spleenqideficiencya7、ndheartliverstagnatedheatsyndromesarehigherthantheothertwogroups(P<0.O5);immuneclearancestategroup,heatandhumidnessretention,liverdepressionandqistagnationsyndromesarefrequent,comparedwiththeother(P<0.05),immunedeficiencystategroup,yindeficiencyofliverandkidney,Qiandy8、indeficiencyandliverblooddeficiencysyndromesaremorethantheothertWOgroups(P<0.05).Conclusion:ChronicHBVinfectionimmunitygroup
3、),广西科学研究与技术开发计划项目(桂科攻No.10124001B),广西卫生厅医疗卫生计划课题(No.Z2007190)StudyofdifferentimmunestatusofmainTCMsyndromesofchronicHBVinfectionYANGLi·sha,LIANGZhi—qing,FANJian—wei,WULin—ling,SUYuan—ying,ZHANGBing(DepartmentofTCM,AffiliatedHospitalofGuilinMedicalUniversity,Guilin5410
4、01,China)Abstract:Objective:ThronghtheresearchofdiferentimmunestatesyndromesofchronicHBVinfection,tounderstandthedifferentimmunestatusofTCMsyndromedistribution.Methods:Usingimmunologicalclassification,syndromesandclinicalepidemiologysurveymethod,select200HBVpatientsof
5、differentstatesamongimmunetolerance,immuneclearanceandimmunedeficiencyrespectively,andhaveamainsyndromeanalysis.Results:ThreedifferentimmunestatesofchronicHBVinfectionallhavesyndromesofliverdepressionandspleendeficiency,yindeficiencyofliverandkidney,liverqistagnation,
6、accumulationofdamp—heat,spleenqideficiency,qiandyindeficiency,heartandliverstagnatedheat,deficiencyofliverblood,lungandspleenqideficiency,bloodstasis,deficiencyofspleenandkidneyyang.Inimmunetolerancegroup,incidencesofliverdepressionspleendeficiency,spleenqideficiencya
7、ndheartliverstagnatedheatsyndromesarehigherthantheothertwogroups(P<0.O5);immuneclearancestategroup,heatandhumidnessretention,liverdepressionandqistagnationsyndromesarefrequent,comparedwiththeother(P<0.05),immunedeficiencystategroup,yindeficiencyofliverandkidney,Qiandy
8、indeficiencyandliverblooddeficiencysyndromesaremorethantheothertWOgroups(P<0.05).Conclusion:ChronicHBVinfectionimmunitygroup
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