欢迎来到天天文库
浏览记录
ID:55059873
大小:186.98 KB
页数:3页
时间:2020-05-08
《不同中医证型慢性乙型肝炎轻度患者肝组织病理研究-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中西医结合肝病杂志2014年第24卷第1期·7··临床论著·doi:10.3969/j.issn.1005-0264.2014.01.002不同中医证型慢性乙型肝炎轻度患者肝组织病理研究朱肖鸿陈丹丹周萍宋诗雅孙慧伶王树民1.浙江中医药大学附属第一医院感染科(浙江杭州,310006)2.浙江省丽水市人民医院摘要目的:研究不同中医证型的慢性乙型肝炎(CHB)轻度患者肝组织病理特点,并探讨其临床意义。方法:将310例CHB轻度患者进行中医辨证分型,采用Menshini法1秒钟经皮肝穿取肝组织进行炎症和纤维化程度判断,并与车祸死亡正常人作对照,同
2、时荧光定量PCR法检测患者血清HBVDNA水平。结果:①肝组织炎症≥G2、肝纤维化≥s2等级的患者年龄明显高于肝组织炎症3、大越有必要;在控制肝脏炎症方面,辨证治疗应多加倡导,在抗纤维化治疗方面应重视补肾法研究。关键词肝炎,乙型,慢性;中医辨证分型;肝/病理学StudyofliverhistopathologyindiferentChinesemedicinesyndromepatientswithchronichepatitisBZHUXiao—hong,CHENDan—dan,ZHOUP,eta1.DepartmentofInfectiousDisease,TheFirstAffiliatedofHospitalofZhe—jiangChineseMedi4、cineUnivesity(HangzhouZhejiang,310006)ChinaAbstractObjective:TostudypathologicalfeaturesofchronichepatitisBpatientswithmilddiseaseanddifferenttradi—tionalchinesemedicine(TCM)syndrometypes,andtoexploreitsclinicalsignificance.Methods:TheTCMsyndrometypesofthreehundredandtenc5、hronichepatitisBpatientswithmilddiseasewereidentifiedsyndromediferentiation.Asecondpercutane—OUStranshepatichepatictissueinflammationandfibrosisdegreewasjudgedbyMenshinimethod,andcomparedwiththeCaracci-dentdeathofnormalpeople,atthesametimefluorescentquantitativePCRmethodw6、asusedtodetectthelevelofserumHBVDNAinpatientswithCHB.Results:@Patientageofinflammation≥G2andfibrosis≥s2wassignificantlyhigherthanthatofinflammation7、herthannormalgroup,butamongdifferentsyndrometypeswerenotstatisticalsignificance;~Theratiooflivertissuefibrosisdegree≥s2inpatientswithdifferentTCMsyndrometypesweresignificantlyhigherthannor—malgroup,thesyndrometypeofYindeficiencyofliverandkidney,andthespleenkidneyYangdefic8、iencytypewassignificantlyhigherthanthatofliverstagnationandspleendeficiencyanddampheatresistance
3、大越有必要;在控制肝脏炎症方面,辨证治疗应多加倡导,在抗纤维化治疗方面应重视补肾法研究。关键词肝炎,乙型,慢性;中医辨证分型;肝/病理学StudyofliverhistopathologyindiferentChinesemedicinesyndromepatientswithchronichepatitisBZHUXiao—hong,CHENDan—dan,ZHOUP,eta1.DepartmentofInfectiousDisease,TheFirstAffiliatedofHospitalofZhe—jiangChineseMedi
4、cineUnivesity(HangzhouZhejiang,310006)ChinaAbstractObjective:TostudypathologicalfeaturesofchronichepatitisBpatientswithmilddiseaseanddifferenttradi—tionalchinesemedicine(TCM)syndrometypes,andtoexploreitsclinicalsignificance.Methods:TheTCMsyndrometypesofthreehundredandtenc
5、hronichepatitisBpatientswithmilddiseasewereidentifiedsyndromediferentiation.Asecondpercutane—OUStranshepatichepatictissueinflammationandfibrosisdegreewasjudgedbyMenshinimethod,andcomparedwiththeCaracci-dentdeathofnormalpeople,atthesametimefluorescentquantitativePCRmethodw
6、asusedtodetectthelevelofserumHBVDNAinpatientswithCHB.Results:@Patientageofinflammation≥G2andfibrosis≥s2wassignificantlyhigherthanthatofinflammation7、herthannormalgroup,butamongdifferentsyndrometypeswerenotstatisticalsignificance;~Theratiooflivertissuefibrosisdegree≥s2inpatientswithdifferentTCMsyndrometypesweresignificantlyhigherthannor—malgroup,thesyndrometypeofYindeficiencyofliverandkidney,andthespleenkidneyYangdefic8、iencytypewassignificantlyhigherthanthatofliverstagnationandspleendeficiencyanddampheatresistance
7、herthannormalgroup,butamongdifferentsyndrometypeswerenotstatisticalsignificance;~Theratiooflivertissuefibrosisdegree≥s2inpatientswithdifferentTCMsyndrometypesweresignificantlyhigherthannor—malgroup,thesyndrometypeofYindeficiencyofliverandkidney,andthespleenkidneyYangdefic
8、iencytypewassignificantlyhigherthanthatofliverstagnationandspleendeficiencyanddampheatresistance
此文档下载收益归作者所有