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时间:2020-05-07
《双源CT能谱成像在局灶性结节增生和肝癌的诊断与鉴别诊断中的应用价值-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、南昌大学学报(医学版)2013年第53卷第9期JournalofNanchangUniversity(MedicalSciences)2013,Vo1.53No.945双源CT能谱成像在局灶性结节增生和肝癌的诊断与鉴别诊断中的应用价值曾炳亮,林小琪(江西省人民医院CT室,南昌330006)摘要:目的探讨双源CT能谱成像在局灶性结节增生(FNH)和肝癌的诊断与鉴别诊断中的应用价值。方法回顾性分析52例经病理证实的肝脏富血供病变患者(肝癌35例,FNH17例)的双源CT能谱成像(动脉期及门脉期)的系列图像。测量病灶及肝组织等的能谱参数;并计算两期不同能量水
2、平下病灶一肝组织对比噪声比(CNR)、标准化碘浓度(NIC)及病灶与肝组织碘浓度比值(ICRLN)。结果动脉期:FNH与肝癌在4O~120keY的CNR随着能量的升高逐渐减少,均在120keV具有最佳的CNR;NIC及ICRLN值FNH均显著高于肝癌(P<0.05)。门脉期:在4O~120keV,FNH的CNR逐渐减少,在4OkeV具有最佳的CNR,而肝癌则是先增加再逐渐减少,在8OkeV具有最佳的cNR;NIC及ICRLN值FNH均显著高于肝癌(P<0.05)。结论双源CT能谱成像可提高FNH及肝癌的检出及诊断准确率,具有较大的临床价值。关键词:肝癌
3、;局灶性结节增生;体层摄影术,x线计算机;诊断,鉴别中图分类号:R445.2文献标志码:A文章编号:2095-4727(2013)09-0045-03ApplicationofSpectralImagingofDual—sourceCTinDiagnosisandDifferentialDiagnosisofHepat0cellularCarcinomaandFocalNodularHyperplasiaZENGBing-liang,LINXiao-qi(DepartmentofRadiology,thePeople’SHospitalofJiangx
4、iProvince,Nanchang330006,China)ABSTRACT:ObjectiveToexplorethevaluesofspectralimagingofdual—sourceCTindiagnosisanddifferentialdiagnosisofhepat0cellu1arcarcinomaandfocalnodularhyperplasia(FNH).Meth-odsSerialspectralimagesofarterialandportalvenousphasedual—sourceCTwereretrospective
5、—lyanalyzedin52patientswithpathology——confirmedhepaticlesionswithrichbloodsupply(35ca—sesofhepatocellularcarcinomaand17casesofFNH).Thespectralparametersofnormalhepatictissuesandhepaticlesionsweremeasured,andthenormalizediodineconcentration(NIC),lesion—livercontrast—to—noiseratio
6、(CNR)andiodineconcentrationratiooflesion—normalliver(ICRLN)atdifferentenergylevelsweredeterminedduringtheportalvenousphaseandarterialphase.Re-suitsArterialphase:FNHandhepatocellularcarcinomain40~120keYCNRasenergyincreasesgraduallyreduce,inthe120keVhasthebestCNR;NICandICRLNvalues
7、FNHweresignifi—cantlyhigherthanthatofhepatocellularcarcinoma(P<0.05).Portalphase:in4O一120keY,CNRofFNHgraduallyreduce。in40keVhasthebestCNR,andhepatocellularcarcinomaiSin—creasedfirst,thengraduallyreduceinthe80keYhasthebestCNR;NICandICRLNvaluesFNHweresignificantlyhigherthanthatofh
8、epatocellularcarcinoma(P<0.05).ConclusionThe收稿日
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