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时间:2020-05-02
《右美托咪定复合全身麻醉对老年患者围术期的影响及感染预防.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中华医院感染学杂志2013年第23卷第24期ChinJNosocomiolVo1.23No.242013·5997·论著右美托咪定复合全身麻醉对老年患者围术期的影响及感染预防韩晓东,林峥,徐建伟(温州市中心医院麻醉科,浙江温州325000)摘要:目的探讨右美托咪定复合全身麻醉对老年患者围术期的影响,总结感染预防应对策略,为右美托咪定的临床应用以及围术期感染预防提供指导。方法选择2012年6月一2012年12月在医院行腹部手术的6O例老年患者作为研究对象,随机分为观察组与对照组,每组3O例;观察组在麻醉诱导前静脉滴注
2、盐酸右美托咪定注射液,对照组静脉滴注等量生理盐水;麻醉的诱导均采用丙泊酚、芬太尼和维库溴铵,麻醉后均采用静脉自控镇痛。采用双盲法观察并记录患者术后3、6、12、24、48h的视觉模拟评分(VAS)、Ramsay镇静评分以及不良反应情况,采用SPSS软件16.0进行统计分析,计量资料分析采用t检验,计数资料分析采用检验。结果观察组术后6h后的VAS评分以及Ramsay镇静评分结果均明显优于对照组,差异有统计学意义(P<0.05);观察组术后镇痛满意率为93.3,对照组为76.7,差异也有统计学意义(P3、论采用右美托咪定复合全身麻醉与老年患者术后镇痛相互协同,可以起到较好的镇痛效果,且不良反应少;老年围手术期感染的是多因素造成的,应根据老年感染的特点进行积极防治。关键词:右美托咪定;全身麻醉;老年患者;围手术期;感染预防中图分类号:R181.32文献标识码:A文章编号:1005—4529(2013)24—5997—03Effectofdexmedetomidinecombinedwithgeneralanesthesiaonperioperativeinfectionsinsenilepatientsandprev4、entionmeasuresHANXiao—dong,LINZheng,XUJian-wei(WenzhouCentralHospital,Wenzhou,Zejiang325000,China)Abstract:OBJECTIVEToinvestigatetheeffectofdexmedetomidinecombinedwithgeneralanesthesiaonperioper—ativeinfectionsinthesenilepatientsandputforwardcorrespondingpreve5、ntionmeasuressoastoguidetheclinicaluseofdexmedetomidineforthepreventionofperioperativeinfections.METHODSTotally60casesofsenilepatientswhounderwenttheabdominalsurgeryinthehospitalfromJun2012toDec2012werechosenasthestudyobjectsandrandomlydividedintotheobservatio6、ngroupandthecontrolgroup,with30casesineach;theobserva—tiongroupwastreatedwithintravenousinjectionofhydrochloricdexmedetomidinebeforeanesthesiainduction,whilethecontrolgroupwasgiventheequalvolumeofsaline,thentheanesthesiawasinducedwiththeuseofpropofol,fentanyl,7、andvecuronium,allthesubjectsreceivedpatientcontrolledintravenousanalgesiaafteranes—thesia,thedouble—blindmethodwasemployedtoobserveandrecordthevisualanaloguescore(VAS),Ramsaysedationscore,andincidenceofadversereactionsat3,6,12,24,and48hoursafteroperation,thest8、atisticalanalysiswasperformedwittheuseof.SPSS16.0software,themeasurementdatawereanalyzedthroughthet—test,andthecountdatawereanalyzedbythechi-squaretest.RESULTSSixdaysafterthesurger
3、论采用右美托咪定复合全身麻醉与老年患者术后镇痛相互协同,可以起到较好的镇痛效果,且不良反应少;老年围手术期感染的是多因素造成的,应根据老年感染的特点进行积极防治。关键词:右美托咪定;全身麻醉;老年患者;围手术期;感染预防中图分类号:R181.32文献标识码:A文章编号:1005—4529(2013)24—5997—03Effectofdexmedetomidinecombinedwithgeneralanesthesiaonperioperativeinfectionsinsenilepatientsandprev
4、entionmeasuresHANXiao—dong,LINZheng,XUJian-wei(WenzhouCentralHospital,Wenzhou,Zejiang325000,China)Abstract:OBJECTIVEToinvestigatetheeffectofdexmedetomidinecombinedwithgeneralanesthesiaonperioper—ativeinfectionsinthesenilepatientsandputforwardcorrespondingpreve
5、ntionmeasuressoastoguidetheclinicaluseofdexmedetomidineforthepreventionofperioperativeinfections.METHODSTotally60casesofsenilepatientswhounderwenttheabdominalsurgeryinthehospitalfromJun2012toDec2012werechosenasthestudyobjectsandrandomlydividedintotheobservatio
6、ngroupandthecontrolgroup,with30casesineach;theobserva—tiongroupwastreatedwithintravenousinjectionofhydrochloricdexmedetomidinebeforeanesthesiainduction,whilethecontrolgroupwasgiventheequalvolumeofsaline,thentheanesthesiawasinducedwiththeuseofpropofol,fentanyl,
7、andvecuronium,allthesubjectsreceivedpatientcontrolledintravenousanalgesiaafteranes—thesia,thedouble—blindmethodwasemployedtoobserveandrecordthevisualanaloguescore(VAS),Ramsaysedationscore,andincidenceofadversereactionsat3,6,12,24,and48hoursafteroperation,thest
8、atisticalanalysiswasperformedwittheuseof.SPSS16.0software,themeasurementdatawereanalyzedthroughthet—test,andthecountdatawereanalyzedbythechi-squaretest.RESULTSSixdaysafterthesurger
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