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《copd与支气管哮喘合并copd在肺通气功能、气道激发试验及疗效的临床观察》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、维普资讯http://www.cqvip.com2005年7月中国民康医学杂志Jul,2005第l7卷第7期MedicalJournalofChinesePeoplegHealthVo1.17No.7【论著】COPD与支气管哮喘合并COPD在肺通气功能、气道激发试验及疗效的临床观察聂祥毕(贵州省毕节地区人民医院内科,贵州毕节551700)【摘要】目的:通过比较支气管哮喘合并COPD和COPD在肺通气功能、气道激发试验及疗效的特征,以利鉴别诊断和治疗。方法:本文对45例支气管哮喘合并COPD,42例COPD患者进行肺通气
2、功能、气道激发试验及疗效进行对照观察。结果:1.支气管哮喘合并COPD组小气道气流受阻明显较COPD组严重(P<0.001),气道阻力明显增高(P<0001)。2.支气管哮喘合并COPD组100%显示气道激发试验阳性,而COPD组仅为13.5%,COPD组阳性者所需激发剂(组胺)浓度为支气管哮喘合并COPD的350倍,且两者间较少重叠交叉。3,在I临床常规治疗的疗效上看支气管哮喘合并COPD组优于COPD组(P<0.001)。结论:支气管哮喘合并COPD和COPD虽然在II缶床上很相似,但从肺通气功能、气道激发试验及疗
3、效等特征均有显著的差异。【关键词】支气管哮喘;慢性阻塞性肺疾病(COPD);肺通气功能;气道激发试验;吸烟;肺气肿;I晦床疗效[中图分类号】R562.25;R563,3[文献标识码】A[文章编号】0369(2005)07—0339—03T0observationtheCOPDandtheBronchialasthmacombinedwithCOPDAtpulmoaerationfunction,airpassageprovocationtestandcurativeefectinclinicNEIXiang—bi(Bi
4、jiedistricthospitalofpeopleinGuizhouprovince,Bijie551700,China)【Abstract】Objictive:TocomparecharacteristicthattheCOPDandtheBronchialasthmacombinedwithCOPDatpulmoaerationfunction,airpassageprovocationtestandcurativeaffectinclinic,sothatbenefittheantdiastoleandtre
5、atment.Methods:Usethemeasureofcliniccontrolinvestigationtesttocomparetwogrouppatientsconditionsinpulmoaerationfunctiontest,airpassa~provo—cationtestandcurativeeffect.andstatisticalanalysis.Reslllts:1.ThegroupthatBronchialasthmacombinedwithCOPDtakeplaceaircurrent
6、sufocateatsmallairpassagemorethanothergroup(P<0.001).Theairpassa~resistanceraisedmorethanothergroup(P<0.001).2.100%easesofbronchialasthmacombinedwithCOPDgroupindicatepositivechronotropisminairpassageprovoca-tiontest,butthereale13.5%casesinCOPDgroup,thepositiveeh
7、ronotropismofeasesinCOPDgrouprequireconcentrationratioofbooster(beta—imidazolylethylamine)morethan350times,andfewoverlappinganddecussationatconcentrationratiobetweentwogroup.3.Atthecurativeeffectinclinic,thegroupthatBronchialasthmacombinedwithCOPDovermatchtheoth
8、ergroup(P<0.O1).Conclusions:AlthoughBronchialasthmacombinedwithCOPDwasverysimilitudeinclinic,butfromthepulmoaerationfunc—tiontest,airpassageprovocationtestandcurative
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