欢迎来到天天文库
浏览记录
ID:53738456
大小:218.17 KB
页数:3页
时间:2020-04-21
《靶控输注不同浓度瑞芬太尼对无痛人流手术抑制体动丙泊酚EC50及麻醉效果的影响-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、临床麻醉学杂志2013年l1月第29卷第1l期JClinAnesthesiol,November2013,vo1.29,No.1l·1085·.临床研究.靶控输注不同浓度瑞芬太尼对无痛人流手术抑制体动丙泊酚EC5o及麻醉效果的影响范雪梅王平潘楚雄李天佐【摘要】目的探讨无痛人流手术中,靶控输注(TCI)丙泊酚和瑞芬太尼的最佳配伍浓度。方法择期无痛人流患者100例,随机分为五组:对照组(C组),研究组瑞芬太尼浓度分别为0.4ng/ml(R组)、0.6ng/ml(R2组)、0.8ng/ml(组)、1.0ng/ml(组),采用序贯法确定各组术
2、中无体动反应所需丙泊酚的半数有效浓度(Eo)。分别于入室后(T)、意识消失后(Tz)、手术扩张宫颈(T3)、麻醉苏醒(T4)时记录MAP、HR、SpOz;观察记录不良反应发生率及苏醒时间。结果C组、Rl、R2、、组丙泊酚EC5o分别为6.84、6.33、5.25、4.8O、4.53~g/ml。R2、、组丙泊酚EC50明显低于C组,且意识消失时间及苏醒时间明显短于C组(P<0.05或P3、配伍更为安全、有效。复合不同浓度瑞芬太尼时,注意丙泊酚用药的个体化。【关键词】靶控输注;瑞芬太尼;丙泊酚;半数有效浓度MediumeffectiveconcentrationofpropofolrequiredduringpainlessinducedabortionwithdifferentconcentrationofremfentnailbytargetcontrolledinfusionFANXue-mei,WANGPing,PANChu-xiong,L,Tian-ZUO.DepartmentofAnesthesiology,4、BeqingTongrenHospital,CapitalMedicalUniversity,Beijing100730,ChinaCorrespondingauthor:e-mei,Emaif:xmf0308@sin.corn[Abstract]ObjectiveToexploretheoptimalcompatibilityconcentrationofremifentanilandpropofolbyTCIduringpainlessinducedabortion.MethodsOnehundredASA工or1Ipatient5、sundergoingelectivepainlessinducedabortionwererandomlydividedintofivegroups.Theconcentrationofremifentanilutilizedwas0ng/ml(groupC),0.4ng/ml(groupR1),0.6ng/ml(groupRz),0.8ng/ml(group)and1.0ng/ml(group),respectively.SequentialmethodwasappliedtodeterminetheECsoofpropofolo6、feverygroup.MAP,HRandSp()2wererecordedatthetimeenteringtheoperatingroom(T1),lOSSofconsciousness(]r2),dilatationofthecervix()andrecoveryofanesthesia(T4).Sideeffectsandawaketimewerealsorecorded.ResultsEC50ofpropofolingroupsC,Rl,R2,andwere6.84,6.33,5.25,4.80,4.53/~g/ml,res7、pectively.TheEC5oofpropofolingroupsRE,andRwaslowerthaningroupC,andthetimeoflossofconsciousnessandrecoveryweresignificantlyshorterthanthoseingroupC(P~0.05orP%0.01).AndtheincidenceofrespiratorydepressioningroupRwassignificantlyhigherthanthatingroupC(Pd0.05).ConclusionWhen8、theconcentrationofTCIremifentani1is0.6~O.8ng/ml,itissaferandmoreeffectivetouseittogetherwithpropofolinpainless
3、配伍更为安全、有效。复合不同浓度瑞芬太尼时,注意丙泊酚用药的个体化。【关键词】靶控输注;瑞芬太尼;丙泊酚;半数有效浓度MediumeffectiveconcentrationofpropofolrequiredduringpainlessinducedabortionwithdifferentconcentrationofremfentnailbytargetcontrolledinfusionFANXue-mei,WANGPing,PANChu-xiong,L,Tian-ZUO.DepartmentofAnesthesiology,
4、BeqingTongrenHospital,CapitalMedicalUniversity,Beijing100730,ChinaCorrespondingauthor:e-mei,Emaif:xmf0308@sin.corn[Abstract]ObjectiveToexploretheoptimalcompatibilityconcentrationofremifentanilandpropofolbyTCIduringpainlessinducedabortion.MethodsOnehundredASA工or1Ipatient
5、sundergoingelectivepainlessinducedabortionwererandomlydividedintofivegroups.Theconcentrationofremifentanilutilizedwas0ng/ml(groupC),0.4ng/ml(groupR1),0.6ng/ml(groupRz),0.8ng/ml(group)and1.0ng/ml(group),respectively.SequentialmethodwasappliedtodeterminetheECsoofpropofolo
6、feverygroup.MAP,HRandSp()2wererecordedatthetimeenteringtheoperatingroom(T1),lOSSofconsciousness(]r2),dilatationofthecervix()andrecoveryofanesthesia(T4).Sideeffectsandawaketimewerealsorecorded.ResultsEC50ofpropofolingroupsC,Rl,R2,andwere6.84,6.33,5.25,4.80,4.53/~g/ml,res
7、pectively.TheEC5oofpropofolingroupsRE,andRwaslowerthaningroupC,andthetimeoflossofconsciousnessandrecoveryweresignificantlyshorterthanthoseingroupC(P~0.05orP%0.01).AndtheincidenceofrespiratorydepressioningroupRwassignificantlyhigherthanthatingroupC(Pd0.05).ConclusionWhen
8、theconcentrationofTCIremifentani1is0.6~O.8ng/ml,itissaferandmoreeffectivetouseittogetherwithpropofolinpainless
此文档下载收益归作者所有