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1、肺硬化性血管瘤61例的临床病理与外科治疗分析【关键词】肺；皮肤纤维瘤；诊断；外科手术Clinicopathologicalfeaturesandsurgicaltreatmentof61caseswithpulmonarysclerosinghemangiomaYUChangHai,LIJie,LIUYing,WANGTao,DAIWeiMinDepartmentofThoracicSurgery,FirstAffiliatedHospital,PLAGeneralHospital,Beijing100037,China[Abstr
2、act】AIM:Toinvestigatetheclinicopathologicalfeatures,surgicaltreatmentandprognosisofpulmonarysclerosinghemangioma・METHODS:Theclinicopathologicalfeatures,operativetreatmentandprognosisof61patientswithpulmonarysclerosinghemangiomainourhospitaifromJanuary,1970toApril,2005w
3、ereanalyzedretrospectively.RESULTS:Therewere11males(18.03%)and50females(81.97%)・Themeanagewas39.24(15-59)yearsold.The38(62.30%)patientswerefreeofsymptoms・Byradiography,thetumorpresentedasaroundornearlyroundnodule,withuniformdersityin47(77.05%)casesandcalcificationin14(
4、22.95%)cases・Allpatientsreceivedoperation,withoutcomplicationsanddeath・Immunohistochemicalfindingssuggestedthatthetumormightoriginatefromepithelium・Duringpostoperativefollowupofabout8.25years,therewasnorecurrenceormetastasis・CONCLUSION:Itisverydifficulttodiagnosepulmon
5、arysclerosinghemoangiomabeforeoperation,foritmainlydependsonpathologicalexaminationpostoperatively.Agoodprognosiscanbeachievedthroughsurgicaltreatment・[Keywords]lung;dermatofibroma;diagnosis;surgicalprocedures,operative【摘要】目的：探讨肺硬化性血管瘤(PSH)的临床病理特点、外科治疗及其预后情况•方法：回顾分析总结我
6、院197001/200504收治的61例PSH临床病理特点、诊治方法及随访情况.结果：全组男性11例(18.03%),女性50例(81.97%),平均年龄39.24岁；38例(62.30%)无症状•放射影像学表现为边缘清晰的圆形或类圆形软组织结节影，47例(77.05%)密度均匀，14例(22.95%)有钙化；全部行手术治疗，无手术并发症和死亡；术后病理及免疫组化结果证实PSH并支持肿瘤来源于上皮组织；术后平均随访8.25y,无复发、转移.结论：PSH术前诊断困难，确诊主耍依靠术后病理，手术是PSH的有效治疗方法.【关键词】肺；皮肤
7、纤维瘤；诊断；外科手术0引言肺硬化性血管瘤（pulmonarysclerosinghemangioma,PSH）是一种发生在肺实质的少见肿瘤，术前确诊较困难，易误诊为恶性肿瘤，最后确诊依靠病理学检查•我院自197001200504年间共收治的61例PSH,占同期切除肺部肿瘤的2.17%,现就其临床病理特点、诊断与外科治疗等方面进行探讨、分析，以提高对此疾病的认识与诊治能力.1对象和方法1.1对象本组共61（男11,女50）例患者，男：女为1：4.6；年龄15-69（平均39.24）岁・61例中无症状38例，常规查体发现；咳嗽、咯血2
8、3例（咳嗽23例中痰中带血5例，胸闷气短4例，胸痛1例）•查体均无阳性体征.金组均行胸部X线检查，其中40例行CT扫描，13例行增强CT扫描•病变部位：右肺36例（上叶7例、中叶13例、下叶16例）、左肺25例（上叶9例、下叶16例）
