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1、JournalofFelineMedicineandSurgery(2005)7,233e236doi:10.1016/j.jfms.2004.12.001CASEREPORTCutaneouslesionsassociatedwithcoronavirus-inducedvasculitisinacatwithfelineinfectiousperitonitisandconcurrentfelineimmunodeficiencyvirusinfectionMarthaJCannon1*,MalcolmASilkstone2BA,VetMBD
2、SAM(Fel)MRCVSBVScDipAVPMRCVS,3AnjaMKiparDrVetMedDiplECVPMRCVS1OxfordshireCatClinic,LarkmeadThisreportdescribesaclinicalcaseoffelineinfectiousperitonitis(FIP)withVeterinaryGroup,IlgesLane,multisystemicinvolvement,includingmultiplenodularcutaneouslesions,inCholsey,OxonOX107JP,
3、UKacatthatwasco-infectedwithfelinecoronavirusandfelineimmunodeficiency2AbbeyVeterinaryServices,89virus.Theskinlesionswerecausedbyapyogranulomatous-necrotisingdermalQueenSt.,NewtonAbbot,Devonphlebitisandperiphlebitis.ImmunohistologydemonstratedthepresenceofTQ122BG,UKcoronaviru
4、santigeninmacrophageswithintheselesions.3DepartmentofVeterinaryThepathogenesisofFIPinvolvesaviralassociated,disseminatedphlebitisPathology,FacultyofVeterinaryandperiphlebitiswhichcanariseatmanysites.TargetorgansfrequentlyincludeScience,UniversityofLiverpool,theeyes,abdominal
5、organs,pleuralandperitonealmembranes,andcentralCrownStreet,LiverpoolL697ZJ,nervoustissues,butcutaneouslesionshavenotpreviouslybeenreported.UKDateaccepted:14December2004Ó2004ESFMandAAFP.PublishedbyElsevierLtd.Allrightsreserved.1-year-olddomesticshorthaircatwaslateralaspectsof
6、thecat’sneckandtheproximalpresentedwitha2-weekhistoryofforelimbsexhibitedmultiplewell-circumscribedApyrexia,lethargy,inappetenceandslightlyraised,rednodulesofapproximatelyweightloss,sneezing,bilateralnasalandocular2mmdiameter,whichwereassociatedwithdischargeandconjunctivitis
7、.Thesesignshadnotpartialalopecia,butwerenon-painfulandnon-respondedtotreatmentwithamoxycillin/clav-pruritic.ulanicacid(Synulox;Pfizer)ordoxycyclineThemajordifferentialdiagnoseswerediseases(Ronaxan;MerialAnimalHealth).Someim-thatareexpectedtohavemultisystemicinvolve-provementw
8、asseenfollowingtreatmentwithmentandwhichmayinvolveboththeeyeandthedexametha
