资源描述:
《中草药相关肝损伤临床诊疗指南.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、2016y4z³41ų7}Vol41,No.7April,2016·NOTUV·$Æ$A,'+Ç°ÂÈT/CACM0052016$,9GuidelineforDiagnosisandTreatmentofHerbInducedLiverInjury!"!#$%&'()*&!"!#$%&!+$*&doi:10.4268/cjcmm20160701$,(herbinducedliverinjury,HILI)ÉACGClinicalGuideline:thediagnosisandmanagementofÊ$,、ËÌ,ÊÓËÃÍm±。ÎyÏ,ÐÑidiosyncratic
2、druginducedliverinjury2014y。$,¿wÒ±ÓÔÊ,¤¥ÕÖ×á°Å±¥Ø3)V¬â0Ù,HILIkÚÛÜÝÞß,$,àÛÍá±,µ@K)V¬â0H9^J。[1](druginducedliverinjury,DILI)âÏâãäå。òó31$,(herbinducedliverinjury,HILI)HILIm±àÛæ-#,B,àÛ,çB,¥ÉÊ$,、ËÌ,ÊÓËÃÍm±。[2]VSÊf°ÔÕµèàÛ。Êéê°±$,æ-µ32$,ÊÓËÃWm(Jë±HILI¬ÂÈ,ìÀíHILI¥Èî¦èÃßX]c±$,ÊÓËÃYè。ïð,,±Äñòóéê
3、Æ[ôõ,ìZmÂ。[3]HILIöDILI÷ñøÝ。àï,ùV$A,ë4[d]¬>Þß±â0±HILI9,ìúîûüÑ$,ýþ±99ݦ“[d]^±~_、Ëâ¬~(Gradingµ,&'«ÿ%8ðHILIm±!"µ,#ÝHILI&'ofRecommendationAssessment,DevelopmentandEvaluation,¬$¢%,]VS,,&ê±mÂ,¦O'GRADE)ÅÆ”[4],ì[d]±^`(*1)¬=A'>Ö$A,()»*+,m×è-B./d0。±Þß(*2)Ön~_,¿[d]Yabc_óÂd。ÊHILI¿¬$123B45678,99:/¿b;
4、<=A'>±?+@¥ABØÙ。*1GRADEÅÆ[e¾è^1CTable1ThestrengthofrecommendationdefinedbyGRADE9ÂÈâD$,±EF、[e¾-°fgÊG¹。e[(1^)úîhijklmnopüon9ÂÈHI$,、ËÌ,ÊÓËÃÍm±;qµ[(2^)no¥îâprsÞßÝt±>uhinoûü±。2µÍ^J@K^Jì9^J±ÉL¥Mê±。NÉå{*2GRADEÅÆ>ÞßÊÓâ0Table2ThequalityofevidencedefinedbyGRADE}±Í^J,Obå{}±P9H9^J。NÉ¥å{}±Í^J,ÓQ¥P9(RS
5、bB±ATU)H>^`â09^J。ÝÞß(A)vwîv_x±ÉyzÎXç±Éy,Ö[Í«¬ç¥M{T
6、_xÉy±Mv¾$ÆA'+O'+,µO'"2015y10z$èÞß(B)ì_x±Éyîv¹¾$è,_xyBM{zÎXm±《,µ$9》。çy,}~¿ü¥¦±M{µ,Ö[Í«¬BMReliabilityoftheRousselUclafCausalityAssessmentMethod{T
7、_xÉy±Mv¾forassessingcausalityindruginducedliverinjury2008y。tÞß(C)ì_x±Éy±îv¹¾BC,_xyÑXçyM{¥¦。Ö[Í«¬
8、BM{T
9、_xÉyGRADEg0"m±GradingofRecommendation±Mv¾Assessment,DevelopmentandEvaluation(GRADE)ÅÆtÞß(D)ì_x±ÉyBvS,_xyÑXçyM2004y。{Øw¥¦。ìÉy±f_x¥îâ·1165·2016y4z³41ų7}Vol41,No.7April,20165GnO'Þ,]c$,Ð,ÑÒ、.ÎǬÓÂhÛèÔ.ÕÂ[2223]51HILImO§Ím¾。C8~éìDILIÊHILImO±Gn62I¥VSO'=>,±B=>ÉìâFJ[âOþ¨8mO$$,IÖ=$ASs,Ø>×s$;
10、,"。±k_。ÊvQ)µÊvàÛ,HILImOòDILI,ì、Ãß¹Ø、ÙÚ<,hÛ,Ma8w$Ü[5]_x,HILIu°mO~Ìb,{Æx$,¿O。,¥ì(Ý)、ÕwÃßp¹、,ÙÚ¥èM[24]bB]c,$bö±÷ñ。{øÅǶ。52HILIöDILI±÷ñ63ûüf°àÛHILI¿DILIbö÷ñ¿¥¦%¬FJ±kÚÔÕ°Þ、1iÜO、ÞWÔÕèàÛM{øÅ[613],M{Ñ^U$Sµ«¬¬x[25]Ƕ。$SHILI<`¢%¥[B。ïð,çÑ]c64$K,UV,±ÆxóB。À