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1、曲马多9哌替喘治疗剖宫产术中寒颤的比较［摘耍］冃的探讨曲马多与哌替噪在治疗剖宫产术中寒颤的效果。方法选择拟行剖宫产术、ASAI〜II级、年龄20〜35岁、体重54〜86kg、无心肺系统疾病的足月产妇80例，随机分成T组(］11
2、马多组)与P组(哌替唳组)，两组均行腰侦联合麻醉，取出胎儿后出现寒颤患者T组给予曲马多1mg/kg丁•莫非氏管滴入，P组给予哌替咙1mg/kg于莫非氏管滴入，观察记录寒颤停止的时间、治疗寒颤的效果与恵者BP、HR、RR、SP02的变化以及药物不良反应。结果在用药后寒颤消失患者分别为T组37例(92.5%),P组38例(95%),两组比较无统计学意义，BP、HR、RR两
3、纟R比较差异无统计学意义(P>0.05),但P纽的起效时间(8.5±2,5)min较T组(3.8+0.95)min缓慢，P组中SPO2有8例低于95%,T组无SPO2下降，两组比较差界有统计学意义(P<0.05)。两组的不良反应差异无统计学意义(P>0.05)o结论静脉注射曲马多与哌替旋均能冇效抑制剖宫产术中的寒颤反应，但曲马多起效时间快，呼吸抑制少，更适于治疗剖宫产术中的寒颤反应。［关键词］曲马多；哌替喘；剖宫产；寒颤［中图分类号］R614［文献标识码］B［文章编号］1673-9701(2012)03-0154-02Tramadolandpethidineinthetreatmentofs
4、hiveringmorecesareansectionZHUWeijianWUXiaomeiLIUQianDepartmentofAnesthesiology,GuangdongProvinccZhuhaiCityXiangzhouDistrictNanpingHospital,Zhuhai519060,China［Abstract］ObjectiveToinvestigatetheTramadolandpethidineinthetreatmentofshiveringeffectofcesareansection.MethodsProposedcesareansection,ASAI-I
5、I,aged20-35yearsold,weighing54-86kg,nofull-termmaternalheartandlungdiseases,80caseswerenmdomlydividedintogroupT(tramadolgroup)andthePgroup(pethidinegroup),twogroupsunderwentepiduralanesthesia,toremovethebabyafterthechillsofgroupTpatientsgiventramadolcouldventuriinfusionat1mg/kg,Pgroupwasgivenpethid
6、ine1mg/kgoncouldventuriinfusion,observedandrecordedthetimetostopshivering,shiveringeffectoftreatment,patientswithBP,HR,RR,SP02changosandadversedrugreactions.ResultsInthedisappearanceofshiveringinpatientsaftertreatmentthetwogroupswereTgroup,37cases(92・5%),Pgroup,38patients(95%),showednosignificantdi
7、fference,BP,HR,RRshowednosignificantdifference(P>0.05),buttheonsettimeofPgroup(8.5±2.5)minthantheTgroup(3.8±0.95)minslow,Pgroup,8patientsSPO2lessthan95%,TwasnoSP02decreased,thetwogroupstherewasasignificantdifference(P<0.05).Thetwogroupsnosignificantadversereactionsdifference(P>0.05).ConelusionIntra
8、venousTramadolandpethidinecaneffectivelyinhibittheshiveringresponseinthecesareansection,buttheonsettimetramadolfast,lessrespiratorydepression,cesareansectionismoresuitableforthetreatmentofshiveringresponse.
