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时间:2019-10-18
《临床医学毕业论文椎旁神经阻滞在开胸手术中的临床应用》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、XX大学毕业论文椎旁神经阻滞在开胸手术中的临床应用姓名:2014年6月25日【摘要】目的寻求更好的用于开胸手术的麻醉方法。方法选择50例ASAI〜II级择期行开胸手术的病人,随机双肓对照法分为全麻复合椎旁神经阻滞(P)组(n=23)和全身麻醉(G)组(n=27)。测定血中皮质醇(Cor)和血管紧张素II(Angll)的含量;术屮监测血压、心率;记录异内酚、芬太尼的用量(不包括诱导量),异内酚持续泵入的时间及手术开始至结束的时间;记录患者在麻醉恢复室的恢复时间和烦躁的发生情况;采用视觉模拟评分(VAS)(患者静止状态和咳嗽时)记录
2、术后伤I」疼痛程度。结果①在切皮后30min和术后1d时P组血中的Cor含量显著低于G组(P<0.01);P组血中的Angll含量在切皮后各吋间点均显著低于G组(PV0.01)。②P组血流动力学平稳,在切皮后各吋间点的血压显著低于G组(PV0.01)。③P组术中丙泊酚和芬太尼用量、术毕带管冋PACU的病人数和烦躁的发生率明显低于G组,恢复时间较G组显著缩短(P<0.05或P<0.01)o④静止状态和咳嗽时的VAS评分P组均显著低于G组(P<0.05,P<0.01)o结论全身麻醉复合椎旁阻滞用于开胸手术是可取的麻醉方法。【关键词】
3、椎旁神经阻滞全身麻醉胸科手术[Abstract】ObjectiveToinvestigatetheeffectofthoracicparavertebralblockcombinedwithgeneralanesthesiaforthoracotomy.MethodsFiftypatients(ASAIII),scheduledforselectedthoracicsurgicaloperation,weredividedbyrandomizeddoubleblindcontroltrialintotwogroups:parav
4、ertebralblockcombinedwithgeneralanesthesia(P)group(n=23)andgeneralanesthesia(G)group(n=27).ThcinformationincludedscrumconcentrationofcortisolandangiotensinII,MAP,HR,dosageofpropofolandfentanyl(excludeinductivedosage),timeofoperationandpropofolpumping,timeofrecoveryan
5、doccurrenceofirritabilityofpatientsinPACU,visualanalogscale(VAS).Results①TheconcentrationofCoringroupPwassignificantlylowerthanthatingroupGat30minafterskinincisionand1dafteroperation(P<0.01),TheconcentrationofAngiotensinIIingroupPwassignificantlylowerthanthatingroupG
6、ateveryinvestigatedtimeafterskinincision(P<0.01).②IngroupPthebloodhemodynamicswasstable,thebloodpressurewassignificantlylowerthanthatingroupGattheeveryinvestigatedtimeafterskinincision(P<0.01).③IngroupPthedosageofpropofolandfentanylandthenumberofpatientswithintubatio
7、nafteroperationandoccurrenceofirritabilityinPACUweresignificantlylowerthanthatingroupG,TimeofrecoveryofissignificantlyshorterthanthatofgroupG(P<0.05orP<0.01).④TheVASbothatrestandatcoughingofgroupPwassignificantlylowerthanthatofgroupG(P<0.05,P<0.01).ConclusionThoracic
8、paravertebralblockcombinedwithgeneralanesthesiaisagoodwayforthoracicoperation.【Keywords】paravertebralblock,generalanaesthesia,thora
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