内科药物治疗联合无创正压通气治疗COPD合并重症呼吸衰竭临床疗效观察

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1、内科药物治疗联合无创正压通气治疗COPD合并重症呼吸衰竭临床疗效观察【摘要】目的研究慢性阻塞性肺疾病（COPD）合并重症呼吸衰竭老年患者采用无创正压通气（NIPPV）治疗的临床效果。方法128例COPD合并重症呼吸衰竭老年患者,按随机数字表法分为对照组和观察组，各64例。对照组患者采用常规内科药物治疗，观察组患者在对照组治疗基础上联合NIPPV治疗。观察两组患者治疗效果、血气情况、肺功能以及并发症发生情况。结果观察组治疗总有效率为96.88%,高于对照组的85.94%,差异具有统计学意义（x2=4.873,PO.05）o结论NIPPV治疗COPD合并重症呼吸衰竭患者效果显著，明显改善呼吸功能

2、和肺功能，不增加并发症发生率，值得临床应用及推广【关键词】慢性阻塞性肺疾病；呼吸衰竭；无创正压通❷猱涣菩❷D0I：10.14163/j.cnki.11-5547/r.2016.33.012Observationofclinicaleffectbyinternalmedicationcombinedwithnon-invasivepositivepressureventilationinthetreatmentofCOPDcomplicatedwithsevererespiratoryfailureWANGXiao-dong.DepartmentofEmergency,LiaoningKazu

3、oCountyCentralHospital,Chaoyang122300,China[Abstract】ObjectiveToresearchclinicaleffectbynon-invasivepositivepressureventilation(NIPPV)inthetreatmentofsenilepatientsofchronicobstructivepulmonarydisease(COPD)complicatedwithsevererespiratoryfailure・MethodsAtotalof128senilepatientsofCOPDcomplicatedwith

4、severerespiratoryfailureweredividedbyrandomnumbertableintocontrolgroupandobservationgroup,with64casesineachgroup・Thecontrolgroupreceivedconventionalinternalmedicationfortreatment,andtheobservationgroupalsoreceivedNIPPVforcombinedtreatment.Observationwasmadeoncurativeeffect,bloodgascondition,pulmona

5、ryfunctionandcomplicationsinbothgroups・ResuItsTheobservationgrouphadtotaleffectiverateas96.88%,whichwashigherthan85.94%inthecontrolgroup,andthedifferencehadstatisticalsignificance(x2=4.873,P0・05)・ConclusionNIPPVshowspreciseeffectintreatingCOPDcomplicatedwithsevererespiratoryfailurepatients.Thismeth

6、odcanremarkablyimproverespiratoryandpulmonaryfunction,withoutincreasedincidenceofcomplications.Itisworthclinicalapplicationandpromotion.[Keywords]Chronicobstruetivepulmonarydisease；Respiratoryfailure；Non-invasivepositivepressureventilation；Curativeeffect慢性阻塞性肺疾病(chronicobstructivepulmonary-disease,

7、COPD)是临床常见的呼吸内科疾病，常见于老年群体[1]。呼吸衰竭是COPD较为严重的并发症之一，致死率较高，若不及时有效治疗，则严重威胁患者生命安全。因此如何有效安全的治疗COPD合并重症呼吸衰竭的患者成为人们关注的重点。近年来无创正压通气(non-invasivepositivepressureventilation,NIPPV)的出现为呼吸功能衰竭患者提供了治疗方法，避免了传统气管切开的并发症，成为目前