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1、2016欧洲心脏病学会欧洲动脉粥样硬化学会血脂异常管理指南解读2016年8月ESC于意大利首都罗马召开2016年年会期间发布了备受瞩目的《2016欧洲心脏病学会/欧洲动脉粥样硬化学会血脂异常管理指南》坚持总体的心血管风险评估扩大风险评估及极高危人群范畴PARTONE核心策略SCORE评分《2016年指南》继续强调评价患者整体心血管风险、强调生活方式改良是管理血脂异常的核心策略对于年龄＞40岁的无心血管病、糖尿病、慢性肾病或家族性高胆固醇血症证据的无症状成年人，建议应用SCORE评分等风险评估系统评估总体心血管风险SCORE评分1.Basedonlarge,r
2、epresentativeEuropeancohortdatasets.2.SCOREisintendedtofacilitateriskestimationapparentlyhealthypersonswithnodocumentedCVD.3.PersonswithdocumentedCVD、type1ortype2diabetes、veryhighlevelsofindividualriskfactors、chronickidneydisease（CKD）areautomaticallyatveryhighorhightotalCVrisk.Nori
3、skestimationmodelsareneededforthemtheyallneedactivemanagementofallriskfactors.SCORE评分4.TheSCOREsystemestimatesthe10-yearcumulativeriskofafirstfatalatheroscleroticevent,whetherheartattack,strokeorotherocclusivearterialdisease,includingsuddencardiacdeath.5.TheSCOREdataindicatethatthe
4、totalCVDeventriskisaboutthreetimeshigherthantheriskoffatalCVDformen,sothataSCOREriskof5%translatesintoaCVDriskof15%oftotal(fatal+non-fatal)hardCVDendpointsthemultiplieris4inwomenandlowerinolderpersons.Howtousetheriskestimationcharts‘Lowrisk’arebasedonage-adjusted2012CVDmortalityrat
5、es(225/100000inmenand,175/100000inwomen)thelow-riskchartsshouldbeconsideredforuseinAustria,Belgium,Cyprus,CzechRepublic,Denmark,Finland,France,Germany,Greece,Iceland,Ireland,Israel,Italy,Luxembourg,Malta,TheNetherlands,Norway,Portugal,SanMarino,Slovenia,Spain,Sweden,Switzerlandandt
6、heUnitedKingdom.Howtousetheriskestimationcharts3.≥450/100000formenor≥350/100000forwomen4.Albania,Algeria,Armenia,Azerbaijan,Belarus,Bulgaria,Egypt,Georgia,Kazakhstan,Kyrgyzstan,Latvia,FYRMacedonia,RepublicofMoldova,RussianFederation,SyrianArabRepublic,Tajikistan,Turkmenistan,Ukrain
7、e,Uzbekistan,BosniaHerzegovina,Croatia,Estonia,Hungary,Lithuania,Montenegro,Morocco,Poland,Romania,Serbia,Slovakia,TunisiaandTurkey.ToYoungPeople1.Youngpeoplewithhighlevelsofriskfactors;alowabsoluteriskmayconcealaveryhighrelativeriskrequiringintensivelifestyleadvice.2.Tomotivateyou
8、ngpeoplenottodelaychanging
