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1、山西省克山病重点地区监测结果分析张向东1杨卫国2段严顺31.山西省地方病防治研究所,山西临汾041000;2临汾市疾病预防控制中心;3吕梁市疾病预防控制中心[摘要]目的了解山西省克山病病情,为防治工作提供科学依据。方法在历史重病区交口、吉县、大宁每县选择1个病区乡,每乡选择1个650人左右的病区村,开展临床查体和心电图描记,同时采集部分居民发样检测内环境硒含量水平。结果①共检查1879人,检出克山病病人68例,总检出率型3.62%。其中慢型克山病病人6例,检出率0.32%;潜在型克山病病人62例,检
2、出率3.30%。②检出异常心电图215例,异常率11.4%。克山病人心电图异常改变以ST-T改变和完全性右束枝传导阻滞为主,分别占到总异常项次的22.4%和20.4%。③克山病病例男女性别比为1:1.06。④儿童和成人发硒含量分别为(0.348±0.167)mg/kg和(0.271±0.064)mg/kg。结论①本次调查山西省克山病检出率高于国家控制标准,但从总体上来说,全省病情基本稳定。②克山病仍是严重的公共卫生问题之一,应该充分认识到防治监测工作的长期性、重要性和艰巨性。[关键词]克山病;病情;
3、心电图;硒AnalysisofsurveyresultsofKeshandiseasekeyareasinShanxiprovinceZHANGXiang-dong*,YANGWei-guo,DUNYan-sun.*DepartmentofIodineDeficiencyDisordersandKen-shanDisease,ShanxiInstituteforEndemicDiseasePreventionandTreatment,Linfen041000,Chian[Abstract]Objec
4、tiveTounderstandtheKeshandiseasestatesinShanxiprovince,toprovidescientificbasisforitpreventionandtreatment.Methods1townshipofdiseaseareasinJiaokou,JiandDaningCountywasselected,1villagewhichhaveabout650residentswaschoseineachtownship.Clinicalexamination
5、andelectrocardiographywereperformedinthosechosenpeopleineachvillage,andsamplesofhairwerecollectedatthesametimeandtheconcentrationofseleniumwasdetected.Results①1879residentswereinvestigatedintotal,68Keshandiseasepatientswerefounded,thetotaldetectionrate
6、was3.62%.Amongthe68people,6werechronicandthedetectionratewas0.32%,62werepotentialandthedetectionratewas3.30%.②215abnormalelectrocardiogramsweredetected,andtheabnormalratewas11.4%.AmongthetotalnumberofabnormalelectrocardiogramchangesinKeshandiseasepatie
7、nts,ST-Tchangeandcompleterightbundlebranchblockwerethemainshows,andtheoccupancyratewere22.4%and20.4%.③Thecontrastofmaleandfemalewas1:1.06.④Theconcentrationofseleniuminthesamplesofchildrenandadultwas(0.348±0.167)and(0.271±0.064)mg/kg.Conclusions①Theresu
8、ltsofthissurveillancepresentthemostseriousdiseasestatusinShanxiprovince.ThedetectedrateofKeshandiseaseishighthanthatofcountrycontrolstandard.Butasawhole,thediseasestatusissteadybasically.②Keshandiseaseisstilloneoftheseriouspublichealthi