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ID:38226762
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时间:2019-05-24
《遗传因素对华法林维持剂量的影响_王婷》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、166中药药理与临床2013;29(4)theroleoflong-termhypergastrinemiaingastriccarcinogenesis.JBiomedBio-gastritis.WorldJGastroenterol.2011;17(13)∶1690~1693technol,2011;2011∶975~9799张金丽,王春浩,周文平,等.慢性萎缩性胃炎6种证型胃镜像和病6王蕾,朱薇,陈楚弟,等.胃镜下慢性萎缩性胃炎诊断准确性研究.中理学表现研究.中医杂志.2012;53(11)∶942~944国全科医学,2012;15(13)∶1464~146810Sanchez-Fa
2、yosCP,MartinRM,PorresCJ.Gastricmucosaasatarget7陈清波,王洪波,徐明垚,等.慢性胃病伴肠上皮化生、胃癌与幽门螺ofpersistentproinflammatoryaggression:pathogenicmodelsofchronicgastri-旋杆菌感染的关系.实用癌症杂志,2010;25(2)∶169~174tis.GastroenterolHepatol,2009;32(4)∶294~3068DaiYC,TangZP,ZhangYL.HowtoassesstheseverityofatrophicEstablishmentofmode
3、lofchronicatrophicgastritisinratsandevaluationofstability1121YaoYao,LinXiaochun,LeiXiaolin,TongLi12(SouthernMedicalUniversity,SchoolofChineseMedicine;OrientPharmaceuticalCompany,Guangzhou510515)Objective:Toestablishamodelofchronicatrophicgastritisinratsandevaluateitsstabilityandsensitivity.Methods
4、:Weestablishedchronicatrophicgastritismodelbyusingdeoxysodiumcholatesolutionwithalcoholasstimulusgastritis.Thepathologicalchangeofgastrictis-suewasevaluationstandard.Ratswererandomlydividedintomodelgroupandcontrolgroupandwerefedroutinelyfor30days.Weevaluatedstabilityofthemodelbypathologyofgastrict
5、issue,scanningelectronmicroscopy,gastrointestinalhormonesecretion,bloodflowofgastricmicrocirculation.Results:Weestablishedrat'smodelfor100dayswithasuccessrateof75%.Withintherecoveryphaseof30days,chron-icatrophicgastritismodelratsrecoveredtosomeextentwithspecificrelatedindicators.Conclusion:Chronic
6、atrophicgastritismodelweremadefor100daysbyusingalcoholincombinationtodeoxysodiumcholateandkeepstablefor30days,providinganidealmodelforpharma-codynamicevaluationofdrugsandclinicalfundamentalresearch.Keywordschronicatrophicgastritismodal(慢性萎缩性胃炎模型);deoxysodiumcholate;stabilityofmodal毷櫴櫴櫴櫴櫴毷櫴櫴毷综述櫴櫴櫴櫴
7、櫴毷*遗传因素对华法林维持剂量的影响**王婷,黄宇虹(天津中医药大学第二附属医院,天津300150)摘要华法林是香豆素类口服抗凝血药,是目前临床上应用于抗凝的首选药物,被广泛应用于预防血栓栓塞,主要用于预防及治疗肺栓塞、深静脉血栓症、冠心病、急性心肌梗死、心脏瓣膜置换术后及心房颤动导致的血栓症。由于个体间的差异比较大,其有效治疗窗较窄,抗凝过度与不足都能引起严重的并发症,容易导致血栓或出血,此问题一直备受医药界关注。本文
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